Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25401 Cgp-60474 GSE70138 ASC Human 24h 1.11uM EID0068
Types Number Response transcription factors
Up-regulation 745 NFKBIB; SMARCC1; BHLHE40; EGR4; SOHLH2; FOSL1; HIPK2; PML; TOPORS; POU3F2; SNAPC4; ZNF696; NKX2-2; ZNF783; MZF1; MNAT1; FLI1; ARID3B; MYCL; STAT2; WDR77; ZNF235; CSDC2; PRDM10; ZNF710; ZBTB48; ASH1L; ZNF324; ZNF3; ZNF8; POU2F1; TFDP2; NRF1; YBX2; TSHZ2; EGR2; TFDP3; NR2C2; E2F5; ARID3A; ZBTB6; CREBZF; ZNF574; TTF1; CBX2; AGO2; FOXA2; HDAC5; CDX2; HOXC4; TBX19; ZNF711; NR1I2; ZNF165; ZNF529; ZNF222; EP300; BPTF; TAF9B; EGR3; ZHX3; NR4A1; CBX7; SFMBT1; EHMT1; RFX2; LHX2; ZNF669; ZBTB39; ZFHX2; KDM4C; CAMTA2; ZNF107; HOXC5; ZSCAN16; ASCL1; MYT1; OVOL1; JUNB; SIX3; TADA2A; PHOX2B; BLM; LMO1; ZNF223; OLIG2; ZKSCAN7; MAPK8IP1; KMT2B; ZNF142; SSX3; PAX6; ZNF510; TRIM33; PGR; SOX5; ZNF225; EVX1; NR6A1; EMX1; NKX2-5; MAFK; HOXC8; THAP10; MED25; CHD7; ZBTB20; ZBTB25; BATF3; RFX1; FOXH1; MXD4; ZNF764; ERBB4; KAT2B; ZSCAN2; HNF1B; EP400; RFX7; GBX1; ASCL3; ZBTB44; MAP3K10; ATF7; NLK; TAF5; ERCC2; IRF5; MXD1; CIITA; E2F4; TAF1A; INSM1; NR5A2; ZNF75D; MLXIP; ZNF778; AFF4; DMRT1; PROP1; MYF6; CDX1; ZFP2; MAK; LHX6; HLF; ZNF571; TLX1; NFKBIA; PHOX2A; HNF1A; ZNF177; ZNF614; BCL11A; ZNF493; ZFP30; NR2E1; HOXB9; HMGXB3; PRDM5; TAF6L; MSL3; NEUROD6; IKZF4; SNAI1; ZNF354A; NHLH1; SMAD9; HINFP; SOX15; THRB; SIM2; RERE; ZSCAN9; ETV3; SSX1; SCAI; VDR; SHOX; PRDM2; REPIN1; SSX7; E2F1; ZNF343; ESR2; ZNF14; ZNF227; MEF2A; TFAP4; CIR1; RBL1; ZNF74; YY1; SATB2; DBP; ZNF180; ZNF771; KLF13; ZNF331; ZNF224; ZNF143; ESRRA; ZNF556; ZXDC; BACH1; EPAS1; HCFC2; NKX6-1; MBD4; PIAS3; RBPJL; ZNF770; SP4; ZNF184; CDK9; ZNF131; ZNF695; HDAC11; TCF21; FOXJ1; NKX2-8; SOX11; PDX1; HOXA3; MEN1; TLX2; ZNF408; ZNF221; ZNF133; ESRRG; CBL; BRIP1; PRDM8; POU2F2; PAX7; ZNF446; FOXC2; GLI1; ZNF473; ZNF202; HNF4A; DLX6; GFI1; ZNF124; NAB2; WT1; HES2; ZNF345; DLX4; TULP2; BRWD1; SOX17; MLLT10; AFF3; HNF4G; ING2; ZNF154; NEUROG3; SPEN; PAX1; TP63; ZNF10; ZNF551; FOXD2; LZTS1; ZNF7; TRAF6; RELB; DOT1L; ALX4; ZNF215; NFRKB; FOXD3; ZNF236; HEYL; NEUROD4; FHL5; NR5A1; RFXAP; SOX21; HOXA11; IRF4; ZNF45; SSBP3; MYT1L; CARF; FOXB1; CBX8; MYB; HAND2; ZNF391; ZNF701; WDHD1; NEUROD2; SP1; ZNF516; TAF1; ZNF507; NFX1; SUPT5H; ZKSCAN3; TAF4B; ZBTB43; ZNF287; MECP2; FEV; KMT2A; ATF6B; IKZF5; FOXN3; ONECUT2; FOXG1; MSX1; AIRE; ZBTB7B; LHX3; MNX1; PLAGL2; HOXA6; ZNF134; ZFP36L2; ZNF41; TOX; ASXL1; ZNF557; ZNF292; BAZ1A; MYOD1; ZNF254; MAFG; HIC1; MBD1; ZNF576; ZNF536; HOXD11; ZNF324B; SPIB; FOXE3; ZNF550; NFIX; KLF15; ZFP37; TTF2; SOX3; ZMYND11; HAND1; RING1; ZNF814; NSD1; MKL1; SIX6; ING1; ZNF219; GCM1; NPAT; ZKSCAN4; PSMC3; HR; ZNF16; CHD2; NR1I3; CEBPZ; TBX2; LHX5; RORC; DYRK1B; LMX1B; MYOG; ZNF250; TRIM25; SNIP1; TRIP11; VENTX; RSF1; MED31; HSF1; ASCL2; KLF6; OVOL2; TUB; CUX1; MTA2; TBX10; MLXIPL; POU3F3; PAX2; ZNF721; DLX2; ZNF668; PRDM1; ZNF211; ZNF248; HESX1; TFAP2B; PRDM13; IRF1; FOXL1; PITX3; HOXA1; GATA1; TCF15; ZNF671; IRF6; ERF; TULP4; PBX2; ZNF112; REXO4; ZNF573; EGR1; ETS2; PPARA; HABP4; SOX12; ZNF85; HOXB8; SMAD5; ZIM2; ZNF200; POU6F1; ZNF492; E2F6; ZNF667; NKX2-1; ZNF22; ACTL6B; ZNF440; CHAF1B; CCNT1; SMARCD1; ZKSCAN8; RAX; MEIS1; POU3F4; BAZ2A; SAP130; TEF; ELK4; GABPA; CIZ1; YAF2; ZNF460; PBX3; MLLT1; ZNF443; CDK8; CEBPE; MTF1; ELF2; SP2; BLZF1; ZNF304; RBBP8; NFE2L3; CCNE1; MAFF; SALL2; SETD3; FOXL2; ZNF562; BARX2; ZNF35; CRX; DLX5; ZNF639; SPI1; ZNF611; ZNF835; POU3F1; YEATS4; ZNF93; FOSB; RORB; WHSC1L1; BNC1; FOXN1; GATA2; PREB; THAP9; ORC2; ZNF549; VPS72; ZNF253; NKX3-2; NPAS1; ZNF234; ZNF79; HOXC11; ZNF350; MDM4; HMBOX1; KLF9; ZNF419; NOCT; KMT2D; PRDM12; IFNB1; PRDM4; KLF7; TFE3; TRIM32; HOXA2; CIC; PPP1R13L; ZNF480; TBX5; NR1D2; ZBTB7C; ADRB2; ZNF682; PRDM14; ZNF264; HMX1; ZMIZ2; ID3; WWC1; TP73; HEY2; ZNF175; POU1F1; ZNF629; BRPF1; ATOH1; TBL1Y; TBX4; PHF8; LBX1; POU4F3; HIVEP3; E2F8; ZSCAN32; ZNF34; ZSCAN18; HIPK3; ZNF749; ZNF506; BRDT; ZNF442; GRIP1; SCRT1; HOXB1; SIX5; SOX1; RFX3; CALR; TRIM27; NKRF; ZNF471; MED14; IRX4; GRHL2; ZKSCAN5; ESR1; NEUROG1; WWP1; HOXD12; SUV39H2; GSC2; EMX2; ZNF816; UBTF; JUN; ESRRB; PRDM9; ARRB1; KLF3; ZNF780B; CNOT3; PRDM16; CREG1; URI1; HDAC9; GMEB1; ELF4; PIAS4; ZNF787; NRL; KLF5; ID4; KDM5C; ZNF205; GCM2; IRF2; HOXC13; ZNF33B; DDX5; L3MBTL1; PHF2; SUPT6H; PRRX1; CASZ1; HOXD9; PAXBP1; LIMD1; HDAC7; EZH1; ZNF362; ZNF155; ZNF407; SIRT2; PIAS1; TFEB; ZNF135; ZNF157; MNDA; CAMTA1; NR4A2; PKNOX1; RARG; MAML3; WHSC1; ACTL6A; DDX54; AFF2; ZBTB16; KLF10; PITX2; ZNF80; ZBTB3; VHL; RXRA; WNT4; HOXD13; MED27; SOX18; DMTF1; ZNF652; HOXA4; SATB1; ONECUT1; CBFA2T3; TFAP2A; YEATS2; ZNF257; SOX14; ZNF552; TBL1XR1; ZNF81; NFATC1; CDIP1; ZNF674; CDX4; ZFHX4; TGFB1; SUPT3H; DACH1; CERS6; NR0B2; ZBED4; ZFY; MED15; ZBED2; POU4F2; NR1H2; NR4A3; CUX2; MED13; DCC; BRCA2; TAL1; ID1; ZNF587; HSF2; PIAS2; POU6F2; NCOA1; PAWR; INSR; SRY; CSDE1; HIC2; TOB1; ZNF329; ZNF239; GFI1B; SKIL; HMGB3; ZNF195; GTF2I; PAX4; MYCN; MYBL1; TCF20; MYBL2; BHLHE41; FOXE1; BCOR; NR1H4; ZEB1; HIPK1; VGLL1; IKZF3; KLF11; TCF7; SPDEF; SKI; UIMC1; ZNF665; ZNF675; ZSCAN31; DAXX; HOXB13; AEBP1; ELF5; NEUROG2; TADA3; NFATC3; E2F2; EN2; FOXM1; ZNF623; AFF1; HOXD3; POLR3C; ING3; ZNF532; ZFP69B; ZNF512B; ISL1; ARNTL2; MYRF; ZBTB38; KLF4; HIVEP2; HLX; CREBL2; NEUROD1; IL16; MEOX2; CREB1; CTNNB1; HOXB2; RUNX1; TCF4; BCL11B; SALL1; GATA4; EYA1; BACH2; ZNF43; SMARCA2; EHF; ZHX2; KDM5D; TXNIP
Down-regulation 191 CEBPA; CDK7; USP22; TSC22D3; ECD; XBP1; RBPMS; UBE2I; PHF20; SMARCD3; FOXO1; TCF25; FOXO3; HDAC2; ZZZ3; MTDH; REST; CTCF; TRIM16; PFDN5; BRD7; WWTR1; BRD8; PCGF2; SMARCE1; HMGN3; AES; TRIM22; PDLIM1; ITGB3BP; TRIP6; SP100; LOXL2; RBM39; CTBP1; ERBB2; CCNH; CHD9; TCERG1; PUF60; ADNP; SMAD6; NUP62; ATF4; PIR; CBFB; CCNC; TLE1; HOXA5; HSBP1; FLNA; TBL1X; RREB1; KAT6A; SCAND1; ZNF263; SNAI2; ZIC1; ATF5; NFYC; ERCC3; RNF10; ELF1; ABL1; MED23; ASH2L; HIF1A; CITED2; SOX4; RNF138; PA2G4; RRN3; PATZ1; TGIF1; FOSL2; ENY2; MITF; SMARCA5; THAP4; EED; ARID4B; FOXJ3; UBE3A; ZNF593; MAZ; HMG20B; HDGF; DDIT3; MEOX1; MMS19; BTF3; CCDC59; HMGB2; STAT1; CNOT1; MAF; PSPC1; BMI1; BNC2; NCOA2; TRIM29; MNT; RAN; PPARG; ZFP36L1; ZNF146; PPARGC1A; SAFB2; C1D; SFPQ; MED4; OSR2; NPAS2; PCGF1; NKX3-1; ARL2BP; ZBTB18; TBPL1; TCEB2; NCOA4; TAF11; TRIM28; NR2C1; TGFB1I1; ATF2; SREBF1; SP110; ZNF432; STAT5A; MLX; MED24; TLE2; TAF1D; DNAJC1; TAF9; CTBP2; NR2F2; TBX3; HLTF; RBFOX2; RAD21; TCEA1; GTF2IRD1; SOX9; NFIB; POU4F1; DEK; CHD1; TFAM; CREB3L1; AHR; GLI3; NRIP1; FHL2; MED1; IRF7; RFXANK; DEAF1; TSC22D2; HOXB6; NR2F6; CNOT2; HBP1; THAP11; FUBP1; VGLL4; CRY1; KAT6B; SIX2; LITAF; CD3D; GTF3A; CRYM; SHOX2; BRD4; PLAGL1; NCOA6; TCF7L1; SMAD1; MED21; YWHAB; ZNF91; CRK; YBX3; MAGED1; POU2AF1; PBX1; RUNX3; BTG1; NR3C1; MTF2