Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25396	Iniparib	GSE70138	ASC	Human	24h	0.37uM	EID0068

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	SUV39H1; FOSB; ZNF544; TSC22D1; NR4A1; HMBOX1; HDAC5; CEBPZ; ZNF586; ZNF134; ZMYND8; ELF5; MED24; KLF6; EPAS1; FOXG1; ZSCAN5A; TFCP2L1; ELK4; MKL2; TOB1; ZNF419; RNF141; TSHZ2; ZNF394; HMGB2; NCOA4; SMARCA1; FOXC1; TBX2; AEBP1; YAF2; ZNF324; TAF9B; TRPS1; LHX6; NFATC3; PCGF3; EGR3; AGO2; ZNF587; PSMC3; IKZF5; MECOM; OLIG2; ADNP2; FUBP1; HLF; MEF2A; DDX5; NFIB; EN1; ZNF211; PEX2; GTF2I; RBBP7; ITGB3BP; NR1H2; HEY1; JUNB; NR4A2; TRIM24; ATF7IP; ZNF611; FOS; ZNF266; NFIX; KLF1; SATB2; HTATIP2; GATA3; ZNF83; LMCD1; HIPK2; NR1H3; CENPF; BCLAF1; PRRX1; FOXJ1; ZNF665; JUND; CREBZF; NFX1; YWHAB; SCAND1; NCOA1; MXD4; NR4A3; EYA1; KLF9; ZSCAN18; FOXM1; LITAF; EYA2; HOXC10; ZEB1; SPIB; HIPK3; ZNF331; SSX1; ERBB4; SMARCA2; IRF6; HOXD1; AHR; HEY2; CTR9; BASP1; ERG; ZKSCAN1; TCF4; PBX3; ATF3; ZBTB20; KLF2; EMX2; KDM5D; HOXC6
Down-regulation	120	XBP1; ARID1A; ETV5; SREBF1; BNC2; MDM2; NFE2L3; TGIF1; NCOR1; PCGF2; DEK; ZNF148; SRF; MED15; HDGF; ZNF410; ZNF268; CERS6; NKX2-1; ATF5; CUX2; PLAG1; LOXL2; TCEA1; MYCN; BCL6; BACH2; MAX; RSF1; ZIC3; TERF1; RNF111; DDIT3; PITX2; ZNF12; RYBP; ISL1; RORA; SMAD6; GATA6; BCL10; TGFB1I1; MED13; GTF2IRD1; IRF4; ZNF22; CREB5; PAX9; HOXD10; ZNF91; ZNF232; BCL11B; ZNF32; CTBP2; ZNF654; PITX1; ST18; TAF9; CRY1; CD3D; FOXO1; HOXA10; ZEB2; TLE2; NEUROD1; SMARCB1; AES; MEOX1; KLF11; ZNF257; PBRM1; ATF4; PRDM1; YAP1; FOXN3; SOX18; ZNF423; HOXB6; THAP7; OSR2; IRF7; INSR; BARX1; ELF1; JARID2; SALL2; IRF1; IL16; LEF1; KLF5; HOXB7; FOXD1; GFI1; ELK3; E2F5; ZNF217; MLX; POU2AF1; IFI16; MEIS2; TRIM22; ZNF532; NFAT5; ING3; ZBTB1; FOXE1; DACH1; FLNA; MSX1; PTTG1; ZBTB16; HDAC9; INSM1; ZBTB38; ZBTB18; ZFP36L1; GATA2; NR3C1; E2F2; CREB1