Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25390 Ku-60019 GSE70138 ASC Human 24h 0.37uM EID0068
Types Number Response transcription factors
Up-regulation 36 CEBPZ; SUV39H1; DMTF1; PFDN5; SALL1; TRRAP; AR; HMGB2; NFIB; HSBP1; TBPL1; RNF4; NCOA4; NR1H2; HOXC10; SIAH2; BTAF1; YBX3; KDM5D; JARID2; KLF9; HOXB2; CTR9; BCLAF1; PTTG1; NR2F2; BMI1; BASP1; TRIM22; HLTF; MAF; ZBTB18; ZIC1; HOXC6; TRIP6; ESR1
Down-regulation 82 NR2F6; SP2; ARID3A; HMBOX1; ZEB1; SP100; ATF5; SP140L; SOX10; ISL1; SF1; FOXO1; ARRB1; GLI3; PUF60; PEG3; AEBP1; ZNF117; KDM5C; CBX4; INSM1; ZNF232; PHOX2B; ATF3; E2F5; ERBB4; ACTL6A; RSF1; CAMTA1; TCF7L2; SP110; CDIP1; VDR; ZNF423; PLAG1; ZNF107; MECOM; SKIL; REL; POU2AF1; HOXD1; ELF4; MEIS2; MEOX2; TFAP2A; SOX11; NFAT5; NR5A2; NR4A3; STAT4; ZNF589; LHX3; HDAC4; ZNF721; TCF21; INSR; BACH2; SIX3; ZNF43; PHIP; TAF4B; EYA1; ERG; SALL2; ASCL1; TAL1; ZNF217; JUP; VGLL4; ZNF165; MYRF; ETS1; DAXX; TOX3; ZNF331; TWIST1; MYBL2; IRF6; DACH1; NFATC3; E2F2; CREB1