Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25389 Ku-60019 GSE70138 ASC Human 24h 1.11uM EID0068
Types Number Response transcription factors
Up-regulation 47 RELB; ELF1; BCL3; RNF6; ZMYM2; TRIM16; SIAH2; RLF; CEBPG; KAT7; BMI1; REST; ZNF432; ERF; TRIM28; NPAS2; ZNF468; MED6; PIR; ZNF532; ZNF430; MAFB; ZNF267; SAP18; CREB3L1; NCOR2; SMARCD3; ZNF443; TRIM29; RBBP8; GTF3A; TFAP2C; IRF8; SNAI2; ZNF652; TWIST1; THAP11; BHLHE41; MAF; MAGED1; KLF5; IFI16; WT1; ESR1; HOXC6; ATF5; TBX3
Down-regulation 87 PRPF6; SMARCA1; HMBOX1; CUX1; CREB3L2; ZNF331; SERTAD2; CAMTA1; SOX12; NKX2-1; NR4A2; NR4A3; TOX; PAX6; CNBP; ZFHX4; SOX11; ZNF334; ZNF175; NR3C2; ARRB1; ERBB4; PRMT2; CBX4; LHX2; SOX10; ACTL6B; FOXF2; GATAD2A; ATF3; NHLH2; EPAS1; INSM1; DEK; BRIP1; NR5A2; PITX1; BRD2; ZNF682; ZNF711; HLF; MXD1; RXRA; MXI1; MDM4; CBX6; DACH1; NLK; ZNF83; ZFPM2; ZNF10; NFE2; TCF21; ZNF512B; TCF7L1; CERS6; TCF7L2; SOX3; NR2F1; SIX3; MEIS2; ZEB1; ZBTB20; HEY2; ID3; TFAP2A; WNT4; NFATC1; PAWR; NEUROD1; PEG3; STAT4; PBX3; HEY1; CBFA2T3; DAXX; FOXE1; ID4; MYBL2; ETS1; TDP2; KDM5D; CREB1; MYBL1; TXNIP; ID1; IKZF1