Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25381 Gsk-461364 GSE70138 ASC Human 24h 0.04uM EID0068
Types Number Response transcription factors
Up-regulation 75 MNAT1; MAF; SATB2; ING2; EMX2; ZNF586; HSBP1; NR3C1; NFE2L1; ITGB3BP; SETD3; FOXF1; TERF2; IRX5; TRIP6; ARNTL; KLF4; ZNF134; PMS1; HOXD1; RYBP; NR1H3; SAP30; ZNF281; HMGB3; KAT2B; SMARCA1; DDIT3; RNF138; ZNF91; NANOG; NKX3-1; ZNF304; SMAD1; NFATC1; FOSB; IRF1; ZNF587; CHD7; CRYM; EGR2; BASP1; CENPF; TDP2; SIX1; CREBL2; HMGN3; PAX6; ESR1; ELF5; NFKB1; ZNF430; ZHX2; PITX1; PTTG1; CREB1; IRF6; HTATIP2; KLF5; BCL11A; ZBTB38; BTG1; ZNF551; OLIG2; MSX1; SOX13; ING3; PEG3; GATA6; BHLHE41; PBX1; IFI16; HEY1; ATF5; MYB
Down-regulation 88 FOSL2; SOHLH2; CEBPD; MEOX2; CHD8; RARB; CITED1; TWIST1; USF2; IRF3; RUNX3; E2F6; BRD8; ARID3A; MEOX1; TLX2; SIM1; CAPN15; NFE2; UBE2I; ARID1A; ZNF205; SP2; ZNF573; SIX2; TCF7; MECOM; SIX6; MNDA; JUND; SIX5; HSF1; PEX2; ZNF217; MDM2; ZBTB18; BCL11B; ZNF200; ZFHX4; CBX5; PNRC1; CRY1; NFE2L2; PRDM1; RBL2; GLI3; PITX2; TAL1; UBE2B; KLF13; NFAT5; ZBTB16; ZNF580; SKI; DLX2; NFIC; SSX1; MXD4; POU2AF1; MAFB; SP110; WT1; ZNF467; ANKRD1; CD3D; TGFB1; EN2; FLNA; TLE4; GTF3A; ID2; SUB1; TGFB1I1; LEF1; CUX2; SMAD5; MEIS2; INSR; BMI1; MYRF; DLX5; ATF3; SOX9; TBX3; NFATC3; IKZF1; MTF2; E2F2