Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25379 Gsk-461364 GSE70138 ASC Human 24h 0.37uM EID0068
Types Number Response transcription factors
Up-regulation 42 SMARCA1; TRIM27; MAX; IRF2; CARHSP1; ZNF410; FLI1; NR0B1; VEZF1; ZBED2; RERE; RBBP4; HOXC4; SAP30; SRCAP; CALR; GATA3; RBBP7; PAX5; STAT6; MEIS1; RBPJ; KLF7; CREB1; SALL2; SMAD1; BACH2; MLX; TRIB3; BBX; JUNB; EMX2; PEG3; ZFP36L2; KLF10; PAX6; ID3; IRF6; PBX1; HOXC6; ZKSCAN1; ATF5
Down-regulation 62 SUPT5H; HABP4; DDX5; ZNF432; MDM2; RUNX3; EDF1; CD3D; ZMYND8; ZNF611; ZNF468; ZNF512B; PHF1; NR3C2; NCOA2; FOXE1; YWHAB; BCL11B; ZNF160; LPIN2; JUND; RSF1; TCF7; INSR; URI1; SERTAD2; TGFB1; BHLHE41; BMI1; HIVEP1; ZBTB18; ZNF211; NR5A2; HEY2; KLF4; ATF3; MYCL; ERG; CBFA2T3; CREB3L1; ZNF721; GFI1; NKX2-1; YBX3; ZSCAN31; FOXL2; PITX2; KLF2; MYB; LEF1; NFAT5; ZEB1; HMGA1; GATA6; WNT4; SMARCA2; BASP1; STAT4; HEY1; E2F2; RELB; NR3C1