Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25377	Gsk-461364	GSE70138	ASC	Human	24h	3.33uM	EID0068

Response Information :

Types	Number	Response transcription factors
Up-regulation	94	SUV39H1; TGIF1; MED7; EGR3; CCNA2; PSMC3IP; HOXA1; ING2; ZMYM2; CITED2; HMGB2; NR3C1; ELK1; TFE3; DLX4; NCOA4; CUX1; REPIN1; GATA4; MEF2A; HOXB7; STAT6; C1D; ZNF263; MLXIP; RNF6; ELF3; ZBTB25; HSF2; CCDC59; KLF10; IRX5; ZMIZ2; AHR; SETD2; POU2AF1; DDX5; TOB1; LEF1; ZNF202; ZNF107; TRRAP; PPARGC1A; KDM2A; HOXC8; POU4F1; CBX3; NR0B1; RNF141; KAT7; MNT; FOXJ2; SP3; RNF14; SAP30; IKBKAP; NFRKB; NCOA1; APEX1; ZBTB1; CCNE1; MYT1L; MAGED1; PIAS3; BLM; NKX2-1; RREB1; CD3D; TCF7L2; SIAH2; GFI1; PHIP; PIAS2; TOX; HOXC10; PTTG1; CENPF; SSX1; HMGB3; NKX2-2; BNC1; HMGN3; ZBTB16; EGR2; TRIP6; KLF9; TFAP2C; MYRF; KDM5D; ZFP36L2; ATF5; NR2F2; HOXC6; BASP1
Down-regulation	98	MECOM; RBPJ; ETV4; CBFB; PRPF6; ZNF573; NFE2L3; PROX1; CREG1; ARID1A; ATF3; GLI2; HMBOX1; DACH1; PBX1; MYF5; HIRA; ETV6; THAP10; TOX3; PA2G4; HSF1; ZNF571; ZNF473; MYCN; SOX11; ZSCAN9; VDR; CNOT3; ZNF331; TCF15; SIRT2; STAT2; ZNF205; SF1; PHOX2B; PEG3; TERF1; NCOR2; HMGA1; ZNF112; SOX9; ZNF557; TEAD3; BRD2; RSF1; MEIS1; NFIB; SLC2A4RG; ZFHX3; HHEX; ESRRG; DEK; RBBP4; PRKDC; MYCL; BAZ2B; ZEB1; PITX1; PHF20; SREBF1; REL; JUND; EHF; MED15; DNAJC1; IRF7; INSM1; RYBP; SIX2; ELF5; TGIF2; SP110; FOXN3; ERG; PURA; ELK3; ZMYND8; ZBED2; TCF4; ZNF165; SHOX2; ETS1; TAL1; PBX3; TWIST1; ZNF43; NFAT5; LITAF; TRPS1; DAXX; ZNF423; ZNF586; NFATC3; MTF2; E2F2; IKZF1; CREB1