Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25375	Mitoxantrone	GSE70138	ASC	Human	24h	10uM	EID0068

Response Information :

Types	Number	Response transcription factors
Up-regulation	72	WDR77; MAZ; ZMYM2; TFDP1; RB1; NPM1; USF2; LZTR1; ATF1; ARL2BP; GTF3A; SETD3; FOS; TCF7; PHF1; SIM2; REPIN1; CSDE1; HIPK1; GCFC2; ARNTL2; MYCBP; MITF; HMGB1; FOSB; ZMYND11; SREBF2; NR4A1; MLXIP; HSBP1; SAP18; AES; HIPK3; YBX3; ACTL6A; RFX5; CREG1; CDK2; GATAD2A; NCOA1; CD3D; TAF6; JUP; RNF6; SATB2; LHX6; EHF; RNF10; LMCD1; GRHL2; CTNNB1; FOXM1; TADA3; NFAT5; BCL11A; PITX1; FOXJ1; PBX3; TWIST1; HLX; ZBTB18; MECOM; ZNF652; CREBL2; ID1; HLTF; TXNIP; FOXF1; EMX2; TAF10; HMG20B; NR2F2
Down-regulation	143	NFKBIA; NFIL3; CDK7; FOXO3; MYC; PUF60; PDLIM1; NUP62; FOXJ3; FHL2; ADNP; CEBPD; DDIT3; BHLHE40; RLF; XBP1; TBPL1; SERTAD2; TGS1; ZBTB11; CEBPZ; ARNTL; ZNF292; ZNF7; SUV39H1; RNF111; CEBPA; NRBF2; GON4L; DPF2; POU2AF1; SOX4; TLE1; IRF2; SAP30; NCOA2; ARID5A; SMAD7; RUNX3; ARID5B; ARID4B; EGR2; BANP; PHF20; ZBTB24; ZZZ3; RORA; SCAND1; TAF1D; SETDB1; TAF9; MED13; SALL1; MNT; RFC1; ZNF217; NR2F6; ID2; USP21; EED; FOXO1; ZNF34; TBP; BCOR; SPEN; HBP1; RYBP; TRIM32; NRIP1; SOX9; PLAGL2; PQBP1; IL16; BRD8; CTR9; KAT7; TLE4; CAMTA1; ZNF281; RNF4; PIAS1; ZBTB25; ZNF189; ZNF267; BHLHE41; CDC5L; MED17; NPAT; SALL2; BLM; BCL10; ZNF232; RBPJ; KLF6; BACH1; SSBP2; ZNF589; ZFP36L2; TERF1; VPS72; KAT6B; PAX5; ZFP36L1; ZNF227; CRYM; DNAJC2; ZBTB16; ZNF146; FOXC1; SP110; IRF4; JARID2; JUNB; TCF7L1; IKBKAP; SOX10; MEIS1; ZNF12; BTG1; HOXB2; TP63; ELF5; ATF3; ASCL1; ELF3; SIX1; AHR; MAGED1; MAFB; SMAD1; MYRF; TRIM29; HEY2; IFI16; HOXD1; STAT4; ZHX2; BASP1; KLF2; NR3C1; MTF2; KDM5D; E2F2