Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25373 Mk-1775 GSE70138 ASC Human 24h 0.12uM EID0068
Types Number Response transcription factors
Up-regulation 91 NFE2L1; MEN1; HDAC5; ATF7IP; TRRAP; KAT6A; DEAF1; RHOA; MZF1; ENO1; TFEC; RNF141; TFEB; WIZ; TSC22D2; ZNF692; ZNF282; PIAS3; SIAH2; AR; BAZ1B; ZKSCAN7; NFIC; CBX6; CREG1; YBX3; CTR9; DDX54; TFCP2L1; AES; IKBKAP; DNAJC2; ARNTL; MED24; CUX1; CHD9; UBE2L3; PLAGL2; SAP18; CITED1; ZNF665; IRF9; NLK; ZNF195; ZNF226; ZNF394; ARID1A; ZNF652; MEF2A; RBL2; DBP; IRF8; SOX4; MED13; ZNF146; MYCL; SIX2; LITAF; TRIP6; FHL2; PITX1; ZBTB38; SALL1; HOXB2; HOXC10; TRIM22; IRF4; STAT6; TLE2; RXRA; MAGED1; ASCL1; NFAT5; ID2; HIRA; RFX5; TLE4; MAF; MSX1; MED21; HMG20B; BCLAF1; TULP4; KDM5D; AFF1; SOX11; VGLL4; CREB1; ETS2; IRF6; BASP1
Down-regulation 109 UBE2I; USP22; EGR3; E2F3; TLE1; PRPF6; PHF1; ZNF217; NFKB2; PSMC3IP; SOHLH2; TAF1A; TBL1XR1; OSR2; SOX2; POU4F1; SP140L; ARID5B; ENY2; PRRX1; ZFPM2; ELF1; UBE3A; TDRD3; AEBP1; ZEB1; TCF21; TWIST1; LEF1; SP110; SKIL; MEOX1; PEX2; ZNF423; PHF20; ARL2BP; NFATC4; PITX2; TGIF2; FUBP1; MITF; AGO2; PQBP1; RXRG; ZNF623; NR4A1; TGFB1I1; WT1; ZNF492; UBE2B; CNBP; ZNF32; ZNF157; SP140; HDAC4; FOXA1; ZNF516; TOB1; NR2F1; ZHX2; ZNF80; ARNT2; ZNF257; TBPL1; ESR1; NR2F6; TOX; SOX18; TSC22D1; ID1; NR5A2; ZBED2; ZNF165; SOX3; SOX13; SOX17; BHLHE41; WNT4; NR0B1; SNAI2; HIVEP2; DAXX; AHR; BNC2; LIN28A; ATF3; HMGA1; KLF2; MEIS2; FOXE1; MECOM; ZNF331; ZEB2; KLF5; STAT4; FOXL2; ID3; ELK3; DACH1; HMGA2; MXI1; TBX3; CBFA2T3; NR4A2; FLNA; MYBL1; ID4; MTF2; E2F2