Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25372	Mk-1775	GSE70138	ASC	Human	24h	0.37uM	EID0068

Response Information :

Types	Number	Response transcription factors
Up-regulation	124	BRCA1; GLI2; RHOA; REPIN1; PCBD1; TRRAP; PIR; DMTF1; ZNF212; JUND; ETV1; ZNF14; SATB1; PMF1; HDAC5; MLXIP; BCL3; ARID1A; CDK7; IRF3; UBP1; IKBKAP; POLR2A; SATB2; CCDC59; SMAD4; ZBTB32; CALR; TRIM22; SP2; FOXD1; ZNF226; ZNF263; SALL1; KAT2A; KDM5D; AES; SETD2; CREG1; TRIM32; ELF5; NFIL3; ZMYM2; MSX1; CUX1; FOSB; NR2E1; CREB3L2; YAP1; NR1H2; CNOT3; HR; ZNF282; IRF8; TGFB1; TLE4; PARP1; ZNF146; ID3; ARID4B; NR3C2; ZNF432; SMAD7; WWTR1; NR1I2; TLE2; PCGF2; CENPB; MYC; STAT6; ZBTB24; HOXA10; CHD9; RXRA; MEF2A; PIAS3; MED23; NLK; SLC2A4RG; ELF1; TRIM16; KLF9; DNAJC2; PHF2; TAF6; AEBP1; LEF1; GATA3; CUX2; JARID2; SMARCB1; MED21; EZH2; CDX1; HMG20B; MED1; PITX1; JUP; MEOX2; SOX4; AFF1; MAF; RFX5; HLF; TCF7L1; FOXL2; OSR2; TSC22D2; EYA2; HLX; JUNB; TCF4; ZBTB38; BCLAF1; ELK3; SMAD5; SOX17; CRYM; VGLL4; TOX3; HOXB6; IFI16; ZIC1; PBX3
Down-regulation	121	CCNH; USP22; XRCC6; WWC1; ARNT2; ZKSCAN3; COPS5; SP100; ZNF165; RBBP8; SOHLH2; ISL1; MYRF; HMBOX1; CDK9; MDM2; ATF4; TFAP2A; TGIF1; SP140; PQBP1; KLF1; PSMC3IP; ZNF184; NFE2; E2F3; MNDA; EP300; TFEC; MNAT1; RAN; TAF11; GON4L; CBX6; NPAS2; FOXC1; FUBP1; BRD8; NFATC4; ZNF606; ETS1; ZFHX4; BHLHE41; CIITA; TWIST1; CARHSP1; ZNF239; TBL1XR1; TFDP2; DAXX; ZNF160; KLF3; ZNF423; ZBTB16; DDIT3; TGIF2; CTBP2; MYBL1; ZNF667; ERG; TOX; ZNF652; MXD1; PRDM14; ZNF593; KLF11; FOXK2; ZNF257; ZNF136; NR1H3; ZNF189; ZMYND8; PRRX1; PHF20; KLF7; WT1; ZNF665; TOB1; PRKDC; SALL2; PHIP; BBX; SREBF1; ZNF331; ZEB2; REL; JAK2; TDP2; ZNF264; SHOX2; LPIN2; GMNN; HMGN3; HOXD1; ANKRD1; HIC2; VPS72; AHR; SMARCA1; BASP1; BNC2; FOXG1; NKX2-2; POU4F1; ZSCAN18; MEIS2; LOXL2; DACH1; LMCD1; INSR; NR2F1; PBX1; TRIM29; ID4; CITED2; ATF3; TBX2; ID1; CREB1; MTF2; E2F2