Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25335 Belinostat GSE70138 ASC Human 24h 10uM EID0067
Types Number Response transcription factors
Up-regulation 79 RUVBL1; BCL3; ID2; PHF20; ZNF184; HLTF; IKZF1; RBL2; TCEA2; SOX4; HDAC2; CDYL; GTF2A2; BBX; FOXO4; SETD3; URI1; BCL10; PSIP1; PMS1; NAB1; TERF1; HIVEP2; ITGB3BP; SMARCD3; ZEB2; RNF111; ARID4A; ZBTB18; CTR9; RHOA; HOXA10; PARP1; VEZF1; JARID2; HSF2; RUVBL2; SP110; HMG20B; MXI1; SIX1; RCOR1; SSBP2; ARNTL; SATB1; NEDD8; SERTAD2; TAF10; PRKDC; IL16; ZBTB11; KDM5B; CRY1; SMARCA1; TBPL1; ASH2L; CRK; TBX3; ELK3; KLF9; SMAD6; BRD4; CERS6; TSC22D1; SATB2; DNMT3B; BHLHE41; ASCL1; MYCL; DACH1; AHR; RUNX3; MNAT1; MAGED1; TOX3; BIRC2; BMI1; LEF1; THAP11
Down-regulation 117 FOXM1; CEBPA; ZBED1; PCBD1; TULP3; HDGF; ARNTL2; PMF1; TFAP2C; HMGB2; FOXJ2; ARNT2; ATN1; FOXF2; RXRA; TGFB1I1; CERS4; YBX3; STAT6; XBP1; KAT2B; CEBPG; CCNA2; IRX4; THAP4; TEAD4; VDR; BCLAF1; BNC1; PPARG; ZEB1; EWSR1; MED13; ATF5; VGLL4; BARX2; ZHX2; ZNF282; ZNF512B; SNAI2; RAD21; NCOA2; E4F1; KLF4; BARX1; ZFP36L2; BAZ1A; INSR; LITAF; ATF1; ARL2BP; PHF2; ZNF264; RRN3; ING3; ZNF557; YEATS4; ZSCAN31; ZBTB20; ELF4; SIX3; YAP1; TP53; SMAD1; NCOR2; TRIM22; HOXB6; POU2AF1; ST18; EN1; PTRF; TRIB3; AGO2; DNAJC2; KLF1; PSMC3; DNMT1; ZMYM2; MEOX2; NFE2; HOXB2; MYBL2; PQBP1; FLI1; RREB1; RBPMS; HDAC9; SIAH2; KAT6B; ATF4; ZBTB16; EGR2; MED1; CEBPD; TCF7L1; HIPK3; CBFA2T3; VGLL1; MEIS2; ELF5; TRPS1; HMGB1; DLX5; MEIS1; PLAGL1; TAL1; MYB; FOXD1; EHF; ERG; TBX2; NKX3-1; MECOM; TRIM29; HEY1; DAXX; SUV39H1