Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25318 Gsk-1059615 GSE70138 ASC Human 24h 3.33uM EID0067
Types Number Response transcription factors
Up-regulation 44 FOXO4; CEBPA; PDLIM1; HOXC6; TSC22D3; MLXIPL; KLF9; CREBL2; ARID4B; BAZ2B; TXNIP; HDAC6; CBFB; NKX2-2; HOXB7; ZNF302; MAF; PBX1; MED23; TLE2; HLTF; TAF10; ZNF266; NR1D2; KLF4; AHR; CEBPD; ZBTB20; HMGA2; TSC22D1; BMI1; MTA1; NR0B1; PSIP1; HTATIP2; RUNX3; BCL11B; ZEB1; CITED2; TOB1; ZBTB38; TP63; NR2F2; ELK3
Down-regulation 39 LITAF; BRCA2; ZNF217; SMAD1; ZNF124; TTF2; ZMYM2; TEAD4; MAFG; RBBP8; FOXK2; RAN; AGO2; FOSL1; PRKDC; SMAD7; BRIP1; ID3; ZNF232; CUX1; PBX3; RYBP; RREB1; LOXL2; POU2AF1; ZNF551; MKL2; CRYM; MECOM; DAXX; CTBP2; VPS72; MYBL1; ATF3; TRPS1; FOXG1; ZNF331; KDM5D; PEG3