Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25272 Vorinostat GSE70138 ASC Human 24h 1.11uM EID0067
Types Number Response transcription factors
Up-regulation 31 ADRB2; STAT5B; HMGA2; SUV39H1; BCL6; KLF4; FOXC1; SMARCE1; OSR2; TFAP2C; RNF141; PQBP1; KLF9; NR2F1; HOXB6; MKL2; DMTF1; SPEN; EMX2; TXNIP; MYRF; ZFP36L1; PAX6; PSIP1; AHR; NR2F2; TRIB3; PIR; ERBB4; SOX9; MYBL1
Down-regulation 32 FOSL2; CRY1; KMT2B; ID3; MED17; ZNF587; TMF1; ING3; ZNF91; LMCD1; ZNF430; IRF7; SSBP2; ID1; ID4; MEOX2; ZNF544; EGR3; PBX3; ZNF551; KLF2; THAP11; NR4A1; KDM5D; DACH1; POU2AF1; FOXD1; TOB1; ZSCAN18; LEF1; TLE4; WT1