Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25261 Unc-1215 GSE70138 ASC Human 24h 1.11uM EID0067
Types Number Response transcription factors
Up-regulation 88 SMARCD2; EPAS1; ADRB2; ST18; INSM1; ZNF165; MBD1; ZHX2; HDAC9; TOX4; SP140; EHF; BARX2; ZNF536; BNC1; HIRA; GATA6; TBX5; KLF6; PBX1; PAX6; OSR2; NCOA3; WNT4; RFX2; KLF9; HNF4G; YAP1; CBFA2T3; ELF5; WWC1; KLF5; ZBTB20; BCL6; ZBED2; HOXA1; NR4A3; ILF2; ZNF611; MEIS2; FOXA2; SMAD4; PRRX1; ZNF665; ZBTB16; TP63; KLF4; NR0B1; TCF21; NKX2-2; VGLL1; AHR; ZNF266; LYL1; TOX3; ATOH1; SIX3; ZSCAN18; HOXD1; RBPMS; IRF6; HOXB2; CTBP2; ZIC3; VPS72; TGIF2; TRIB3; BHLHE41; HHEX; FOXF2; PAWR; BACH2; ZNF91; DACH1; NR5A2; SPDEF; ETS1; MYRF; SPIB; FOXF1; SOX9; MYCL; TRIM29; NEUROD1; PLAGL1; NR2F6; ID4; MYBL1
Down-regulation 52 NRIP1; REPIN1; ZMYM2; EYA2; NFYC; CCNA2; CTNNB1; NCOR2; MSX1; NFKBIA; AFF1; UBP1; RNF111; HDAC1; SUB1; ELF1; CREG1; ZBTB1; POU2AF1; PIR; CBX4; STAT6; ZNF267; SMARCA4; FLNA; GTF3A; MED13; MAFB; KAT2B; NFAT5; SLC2A4RG; LEF1; BRD4; SMAD6; HMGB1; SMAD1; PUF60; MDM2; EGR3; SIAH2; SALL1; CALR; ID3; BRD2; AES; KDM5D; ASCL1; SMARCA2; NR2F2; TSC22D2; KLF2; THAP11