Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25260 Unc-1215 GSE70138 ASC Human 24h 3.33uM EID0067
Types Number Response transcription factors
Up-regulation 70 NCOA2; TGS1; SMAD1; TERF1; SUPT5H; MED13; LHX1; WWC1; GLI3; GTF2I; HOXB6; KDM5C; ARRB1; VPS72; ZNF232; DACH1; ZNF467; CITED1; SOX11; SUPT6H; ERBB4; GLI2; NFATC4; TFAP2C; ST18; ETS1; ELF3; SIX3; ATF3; MYBL1; TRIM24; E2F5; NR2F1; TCF21; TCEA1; TRIM29; ZNF24; NR1H2; E2F8; BHLHE40; EPAS1; ESR1; FOXF2; NR5A2; NFE2; TOX; CHD7; MEIS1; ZIC3; TRIB3; WNT4; HOXB2; SMARCD3; RBBP8; MYCL; MEIS2; ID1; ZFPM2; MYRF; ZEB1; POU2AF1; ID4; FOXF1; NR2F6; TCF7L1; TRPS1; AEBP1; PBX1; WT1; DAXX
Down-regulation 38 TLE1; ZNF468; SOX4; SMAD7; FOSL2; CRY1; TSC22D1; MAF; NFIB; KLF2; HLTF; NR1H3; CTNNB1; MAGED1; STAT5A; HSBP1; ZEB2; TFEC; MAFB; AHR; FHL2; SMARCA2; EGR3; RFX5; MEOX2; KDM5D; TXNIP; SIX1; SMAD3; ENO1; THAP11; YBX3; HTATIP2; TCF4; ELK3; ERG; TRIP6; NR2F2