Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25258 Acy-1215 GSE70138 ASC Human 24h 0.12uM EID0067
Types Number Response transcription factors
Up-regulation 32 TP53; GABPB1; FOXO3; NR4A3; MAFB; SMAD6; AHR; SATB2; PRKDC; TAF11; TFDP2; CUX1; ZNF217; EGR2; PIR; ZFP36L1; EMX2; THAP7; LOXL2; PCGF2; TSC22D1; POU4F1; KLF4; TWIST1; MEIS2; ZEB1; BASP1; DACH1; ERBB4; HTATIP2; HEY1; NR4A2
Down-regulation 30 HDAC9; IRX4; TBX3; BHLHE41; SMARCA4; ASCL1; BIRC2; DDIT3; TAF10; C1QBP; SSBP2; NKX2-2; IFI16; TRIM22; INSR; FOXF2; RBPMS; RFX5; PEG3; ID4; SMARCA2; ZSCAN18; MEIS1; MYB; HOXC10; NKX3-1; IRF6; MAGED1; SOX9; KDM5D