Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25223 Olaparib GSE70138 ASC Human 24h 0.37uM EID0067
Types Number Response transcription factors
Up-regulation 36 E2F2; NFATC3; FOXO3; PHF20; GATAD2A; PFDN5; HOXC6; SMARCD2; MBD2; SIAH2; TXNIP; KLF4; TRIM28; BTG1; SMAD2; BRD2; MED1; SMAD1; KLF9; HTATIP2; ZBTB38; FOXC1; TBL1X; PLAGL1; NR2F2; TLE4; PCGF2; TSC22D2; NR1H2; BASP1; PAX6; MAF; TOB1; ERG; TSC22D1; TWIST1
Down-regulation 58 ZBED4; ZNF268; HDAC9; IRF1; ZNF43; E2F3; ZNF195; ZNF22; ZNF32; ZNF239; TTF2; ZNF74; TOPORS; ZNF93; ZFPM2; CD3D; ZNF623; DEK; PHIP; YAP1; SOX5; TFAP2C; E2F8; FOXF2; SNAI2; ZNF544; ZBED2; ZNF107; BRIP1; SALL2; ETV5; TBX21; SOX13; PLAG1; IFI16; PRKDC; BACH2; ZNF232; PBX3; CHD7; MEIS2; ZEB1; TP63; WT1; NFATC4; NR5A2; GATA6; MYBL1; TBX3; ID3; HOXD1; ATF3; SOX2; HIC2; DAXX; SATB1; HHEX; LEF1