Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25220 Olaparib GSE70138 ASC Human 24h 10uM EID0067
Types Number Response transcription factors
Up-regulation 38 CTNNB1; HDAC7; TSC22D4; HOXC6; TEAD1; RBBP4; PRRX2; FOXO3; TAF10; STAT3; RNF10; BCL3; POLR2A; SFPQ; RNF141; NFAT5; ZNF160; SMAD6; GTF3A; ID2; HLTF; GATA3; TRIM16; ESR1; ASH2L; CTR9; TWIST1; MAFB; CRK; KLF2; MYRF; IFI16; CITED2; DMTF1; HOXB7; HOXB6; ELK3; TXNIP
Down-regulation 59 CREB3; ZNF248; TULP3; HMGB3; SIX3; GFI1; ZNF711; ATN1; MED21; TTF2; ZNF141; ZNF266; FOXM1; EN1; NKX2-1; BCL11A; MKL2; ZNF107; NFATC1; ZNF12; SHOX2; TCF21; RBFOX2; CBFA2T3; NR5A2; NR4A1; ZNF551; FOXG1; CNOT3; CDK2; CD3D; FOXF1; SOX11; TRIB3; PAX5; ZFPM2; DNMT1; FOXN3; TOX; WNT4; TAL1; SMARCB1; RFX5; TOB1; PSIP1; GMNN; MYBL1; YBX3; ZEB1; POU2AF1; SPDEF; ID3; ZNF331; PBX3; HIC2; NR1H2; ID1; ZNF91; TRPS1