Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25193 Gsk-461364 GSE70138 ASC Human 24h 3.33uM EID0067
Types Number Response transcription factors
Up-regulation 29 MAFB; CENPB; SPDEF; ARID4B; ATF4; HNRNPD; TOB1; SALL1; ID1; XBP1; AR; CARHSP1; BRD2; ZNF211; ZFP36L2; HDAC9; FOXN3; KLF11; AFF1; TLE4; BCL11B; MYB; YBX3; NR1H2; TRIB3; ELK3; CITED2; BASP1; LEF1
Down-regulation 75 ZNF160; ZNF721; GATA6; BCL11A; ZBED1; ZNF117; CAMTA1; NR4A3; BHLHE41; ZNF611; NFE2; MEOX2; JUP; ZFHX4; ST18; NR2F6; PROX1; SUZ12; ZBTB20; CTBP2; TBL1XR1; REL; MED12; ZNF93; MECOM; CUX1; CCNE1; ASCL1; IRF7; ZNF587; LYL1; CREM; PIR; ELF3; PLAG1; PITX1; CITED1; STAT3; ZKSCAN1; HOXD1; ZNF589; NR4A1; TWIST1; MYCL; BAZ1A; EGR3; KLF6; WWTR1; PEG3; EYA2; HMGN3; ZNF91; EGR2; TCF21; TAF10; MNDA; TFEC; PLAGL1; NR2E1; ISL1; KLF10; FOXF1; MEIS2; MYCN; INSM1; CRYM; SOX9; ATF3; SMARCA2; ZSCAN18; ETS1; PBX1; DACH1; SATB1; ERBB4