Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25105 Doramapimod GSE70138 SKL Human 24h 0.12uM EID0063
Types Number Response transcription factors
Up-regulation 24 TCF20; POU2F2; PTTG1; CREB3L2; MYCL; HOXC6; PQBP1; PIAS1; RBBP7; TSC22D2; MXD4; AEBP1; MAFB; SHOX2; TRIM32; NFATC3; TBX3; HMGB3; PEG3; INSR; OSR2; ZNF131; ZBTB20; ZNF423
Down-regulation 28 CITED2; ZNF467; IRX5; HOXB6; HEY1; HOXB13; PLAG1; MEF2C; CITED1; ZBTB18; TFAP2C; HDAC9; SREBF1; AR; HOXB2; HOXB7; IRF7; SERTAD2; NFIC; MYB; LOXL2; NKX3-1; PBX1; TGFB1; ID3; WT1; ID1; EGR2