Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25091 Ibrutinib GSE70138 SKL Human 24h 1.11uM EID0063
Types Number Response transcription factors
Up-regulation 20 ETV1; NUP62; SPEN; HES1; FOXA1; ZFHX4; TWIST1; ZBTB38; SAP30; FOXF1; LEF1; TOX3; ZNF432; AHR; PIR; MEIS1; DACH1; BMI1; ASCL1; BASP1
Down-regulation 21 PSMC3; KLF2; TRIP6; TCF7L2; YBX3; CREB3L2; CCNE1; HEY2; LMCD1; PSIP1; CITED2; CDK2; BACH2; FOXO1; HOXB7; ELF5; FOXC1; HOXC10; MYRF; PAX5; TRIM29