Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25025 Nvp-bgj398 GSE70138 SKL Human 24h 0.37uM EID0062
Types Number Response transcription factors
Up-regulation 87 ZNF589; MMS19; CEBPD; STAT3; TRIM28; MXI1; USP22; LMCD1; TGFB1I1; FOXD1; EGR1; NFKBIB; ZNF692; CTBP1; EYA2; ZBTB18; SOX4; MTA1; PITX1; ZMYM2; KAT2A; ADRB2; HES1; PPP1R13L; URI1; SIX2; EDF1; MLXIP; FOSL2; DEK; CARM1; SALL1; CREB3L1; TLE1; BATF; PROX1; MED24; GTF3A; LITAF; PTRF; POU2AF1; ERBB2; CIZ1; SNAI2; ZNF528; HDAC5; FOXO1; MAFB; MDM2; PBX3; TXNIP; ZKSCAN1; TRIM22; ZNF281; ID1; MYCN; SMAD6; BTG1; HLTF; INSR; NEDD8; KLF5; TOX3; PEG3; THAP11; EHF; CHD7; STAT1; COPS2; RBM39; TOB1; ZFP36L1; FLNA; HOXB6; ZEB2; NFATC3; HMG20B; KLF9; TRIP6; PFDN5; ZNF652; ZNF91; LOXL2; ATF5; CRK; MEIS2; IKZF1
Down-regulation 98 MEF2C; HOXB13; DDX5; TDP2; FOXJ2; MAX; ATN1; ACTL6A; NR0B1; ETV1; HDAC9; TFAP2A; PAX6; CNOT6; TULP3; FOXM1; ARID1A; ZNF354A; AHR; BHLHE41; TCF7; TFAP2C; CARHSP1; CCNT1; EWSR1; HOXC13; FOXC1; CBX6; HOXC4; DLX2; ETV4; RERE; NFE2; AGO2; HIPK3; MEF2A; ZNF160; ZNF189; ERG; GMEB1; KLF6; JUND; NKX2-2; TAL1; ZNF611; ZNF721; FOXA1; NPAS2; HOXD13; HOXB7; ZNF623; DAXX; BAZ2B; ZFPM2; EMX2; TAF9B; FOXF2; BCL11B; CREM; NFE2L3; FLI1; ZSCAN18; ZFP36L2; TCF4; HOXD1; CBX2; ELK3; TOX; BAZ2A; HOXC6; HTATIP2; ARNT2; ZBTB20; TWIST1; WNT4; MYBL2; IFI16; SOX17; ELF4; PIR; ZSCAN16; DACH1; NR2F1; GATA3; TLE4; KLF2; ESR1; TSC22D1; SMAD1; MYBL1; E2F2; MTF2; NR3C1; HOXB2; EGR2; GATA2; TCFL5; RELB