Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25024 Nvp-bgj398 GSE70138 SKL Human 24h 1.11uM EID0062
Types Number Response transcription factors
Up-regulation 94 TRIM16; CREB3L1; SOX4; MTA1; ZNF692; HOXA5; TAF6; FOSL2; MSX1; SMARCC2; PAXBP1; MMS19; MED24; PCBD1; ZNF202; NCOR2; TRRAP; NELFB; PBX3; DMTF1; BTG1; LOXL2; NR2F2; TBL1X; MAGED1; TGFB1I1; PCGF2; MLXIP; ALX1; EDF1; PSPC1; ZIC1; NR2C1; SIX2; HOXB2; IRF4; CIZ1; DEK; PLAGL1; TEAD4; REPIN1; HOXB6; JARID2; TCF7L1; SMARCD3; CREG1; ZNF580; FOXD1; ZBTB18; CD3D; SIAH2; HOXB5; RBFOX2; SLC2A4RG; ZKSCAN1; THAP11; UBE2I; CITED1; SOHLH2; HMG20B; RAN; SHOX2; GTF2IRD1; EYA1; PBX1; ZNF146; TOX3; ATF7IP; TRIP6; SSX1; NRIP1; KDM5D; DNAJC2; HEY1; HOXB7; MYCL; ID3; HOXC10; MAF; VGLL4; CUX1; PEG3; IKZF1; ATF4; ZNF652; ZNF91; PSIP1; POU2AF1; MAFB; HOXC6; NFATC3; MEIS2; ATF5; CRK
Down-regulation 112 MEF2C; ETV1; TDP2; LYL1; EPAS1; MEOX2; CARHSP1; ERG; ZFP36L2; RNF14; TFDP1; NFE2; ZNF165; IRX4; HOXB13; SPI1; SFPQ; BBX; NPAS2; SMAD2; DDX5; NFYA; PBRM1; HDAC9; GFI1B; TFAP2A; ATF3; HMGA2; JUND; TOX; NR2E1; CAMTA1; CUX2; HOXD1; TSC22D2; TP73; CRYM; ZNF623; FOXG1; TAF9B; RYBP; FOXA1; FLI1; SOX21; DAXX; TAL1; RXRG; KLF5; TLX2; KLF3; IRF1; BHLHE41; NR4A1; ERBB4; LHX2; FOXJ1; BRD2; SCRT1; ELF3; NLK; PSMC3; CREBZF; MECOM; ARNT2; E2F3; TLE1; MLLT1; ZBTB3; NKX2-2; ESR1; TFDP2; DACH1; FOXD3; EMX2; ZNF75D; ZBTB38; HIVEP2; ID4; ETS2; SOX5; LIMD1; IRF6; ZBTB20; ZNF721; ZNF764; BLM; DLX4; NFIB; IFI16; KLF2; SOX17; VGLL1; WWP1; ELK3; TAF4B; ZSCAN16; PAX5; ZNF124; TP63; WWTR1; DLX5; NR4A2; ZNF423; MYBL2; EGR3; GATA3; MYBL1; MTF2; ELF4; E2F2; TCFL5; GATA2