Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID25012	Idelalisib	GSE70138	SKL	Human	24h	1.11uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	256	NFKBIB; CCNA2; MTA1; SMARCA4; SPDEF; IRF3; STAT3; KAT6A; MKL2; FOXO3; FOSL1; GLI2; EGR1; KAT5; ETV1; BAZ1A; SALL1; ZBTB32; KMT2B; FOXD1; PPARD; RUNX3; NELFB; ZNF692; RXRA; BANP; ARID1A; PARP1; DMTF1; BATF3; KDM5D; FOXG1; RUVBL2; PAX8; CHD8; RBM14; SIM2; NOC2L; BAZ1B; RHOA; LZTR1; GRHL2; DPF2; CHD3; PMF1; THAP11; CIZ1; KDM5B; NR3C1; ZNF337; NFYC; BRCA1; RERE; RFX5; BHLHE40; MLXIP; TRRAP; MNAT1; PRPF6; ARID4B; TCF21; LITAF; SUPT5H; HDAC5; ZIC1; ATF7IP; ZNF574; EGR4; EED; ZBTB40; HTATIP2; SATB2; PKNOX2; HOXC11; ZMIZ2; ZNF131; GTF2F1; FOXF1; SAFB2; PCBD1; NUP62; GON4L; SIAH2; SPEN; HDGF; MLLT10; ZBTB17; ZNF146; CTR9; PRDM13; HOXC10; SCMH1; CUX2; CDK9; CREB1; HLTF; NFE2L2; MLXIPL; HMG20B; BACH2; TRIM25; MTF1; E2F6; KAT2A; ARID5B; ZNF143; TRIM27; NR0B1; ZBTB48; HHEX; MED24; ZNF226; TRIM28; BATF; SAFB; ZBTB24; CBFA2T3; TTF1; NEDD8; TBX19; DEAF1; TRIP6; ZKSCAN5; ST18; NFKB2; CRYM; CIC; ZNF282; CITED1; ZNF783; KDM2A; SHOX2; PAX9; NFYA; NCOR2; THAP1; ZBTB18; PHF8; TAF6; CASZ1; TERF2; ZNF45; JARID2; PDLIM1; ARID3A; HMGA2; STAT6; NFKB1; ERCC2; WWC1; PAXBP1; SP3; ZBED2; HR; URI1; SP140; IRF9; RCOR1; NPAT; ZNF267; MSC; ZNF384; ASXL1; TFCP2; MXD1; ZNF253; MYCN; ELF3; IRF8; REL; PHIP; ARID4A; GTF2I; AIP; SOX12; VDR; LZTS1; TAF1C; IRX4; DBP; WWP1; SOX9; SSX1; TRIM32; EN2; PLAGL1; ERBB4; FOXA1; OVOL2; EGR3; BACH1; TGFB1I1; CARM1; IRF7; ZBTB39; HIVEP1; SFMBT1; PAX6; ZNF107; MDM2; REPIN1; PITX1; INSM1; BAZ2B; NR2F1; ZNF580; CD3D; BASP1; NAB1; SNAPC4; NEUROD1; TRPS1; SNAI1; FOSB; IRX5; LHX2; FLNA; NKX2-2; ZBTB25; ING3; TCFL5; PRDM5; NKX2-1; ZNF671; GATA4; IRF4; E2F8; HOXB2; MNX1; RFX7; ASCL1; PGR; MYB; ZNF225; IRF2; MECOM; SMARCD3; BRIP1; GFI1; ZNF835; RNF10; WDHD1; LHX6; CHAF1B; ZNF180; TAF4B; ZKSCAN1; ZNF227; STAT4; ETS2; NR5A2; ZNF552; PUF60; HOXC6; OLIG2; SUV39H1
Down-regulation	279	ZNF140; ZFPM2; SCAND1; NFIL3; BIRC2; DDX5; TAF7; USP22; KLF5; EPAS1; ZNF532; ID3; ZMIZ1; CEBPD; TRIB3; BBX; TBX3; ZNF268; ZMYND8; CTBP2; PHF20; RAN; TDP2; TOX; NR2F6; ATF3; CCDC59; CARHSP1; ACTL6A; TAF11; IKBKAP; PRDM4; HES1; DDIT3; EMX2; MEOX2; CSDE1; PBX3; CEBPG; XBP1; KLF4; PEX2; AHR; KLF3; ZSCAN12; TBPL1; UBE2B; RNF6; ZNF331; ZNF16; FOS; RYBP; ZNF189; NR1D2; SMAD6; PTRF; MEF2A; ZNF354A; CERS6; PAWR; ATF4; TLE1; TEAD4; ZNF84; ARL2BP; GBX2; ZNF432; PRKDC; TULP3; FOXO1; ZNF44; VPS72; PBRM1; NR4A2; BRD2; CBX3; ZFP36L2; TAF12; ERG; ETS1; SMARCC2; ZNF562; SMARCE1; ZNF32; ZNF669; ABL1; THAP4; RXRG; JUNB; TWIST1; ZNF415; PQBP1; ZNF623; XRCC6; SFPQ; EZH2; TSC22D3; JUND; C1QBP; THAP10; NFE2L1; EHMT2; ATF5; PHOX2B; SMAD7; SMAD3; PEG3; BTF3; RNF138; ARNT2; TERF1; ZNF43; MYRF; FOXJ3; ID2; SAP18; LIN28A; ZNF250; NR2C1; ZNF148; SNAI2; HOXD1; ZNF232; TCEA1; SP100; MAFF; WT1; ZSCAN31; UBE3A; TCF7L2; TSC22D2; TSHZ2; RFC1; HOXA10; REST; TRAK1; CREB3; ZFHX3; PRRX1; TAL1; RRN3; HIC2; ZSCAN18; MXI1; LOXL2; ZNF536; BHLHE41; RAD21; TGIF2; HOXB13; ISL1; HMGB1; ZBED4; ZNF23; RUNX1; ARNT; CBFB; KLF7; SIX3; ZNF665; MDFI; ZNF195; PSIP1; DLX2; HSF1; HMGB2; MAGED1; CBFA2T2; TCEB2; ZNF423; HOXA7; NPM1; YWHAB; PBX1; CTNNB1; BAZ2A; ZBTB38; HOXD3; NONO; SETD3; ZNF91; HIRA; SMARCA1; PRDM12; COPS5; NFYB; KLF1; ZNF3; ZNF281; DACH1; CDYL; ZEB2; POU4F3; HDAC9; ATF2; PCGF2; GATAD2A; ZNF7; VGLL4; ZEB1; RNF4; PSMC3; JUP; NANOG; RORB; TOB1; HMGA1; MYCL; ASH2L; HOXB7; CEBPB; SOX10; TRIM29; MTDH; EN1; CALR; MEF2C; KLF2; TLE4; MYT1; PHOX2A; APEX1; HDAC4; DEK; ZNF302; GFI1B; TCF4; AEBP1; CCNT1; RBFOX2; UBE2I; HIF1A; MED1; CREBL2; ZNF667; FOXM1; OSR2; FOXF2; GATA6; ARNTL2; IRF1; UBTF; TRIM16; TGIF1; ZFHX4; ELF1; ETV5; CBX7; HSBP1; FOSL2; ID1; ZNF160; MAF; CREM; CREB3L1; TTF2; ZNF304; ZNF124; FLI1; TAF1A; TBX21; MEIS2; CNBP; MEIS1; BTG1; FOXN3; HEY2; KDM5A; NRIP1; ZSCAN16; YAP1; WWTR1; CRK; HMGB3; KLF13; MED14; ZNF551; MTF2; E2F2