Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID25004 Bms-509744 GSE70138 SKL Human 24h 0.12uM EID0062
Types Number Response transcription factors
Up-regulation 64 TBX3; IKBKAP; DDX5; NR2C1; MTF2; CTR9; TGFB1I1; BPTF; NPM1; TRIM29; SIM2; SUPT4H1; MAZ; ZBED2; MSX1; TAF11; ZNF468; YAP1; ZNF44; CNBP; KAT6B; RAN; ZNF430; PNRC1; ZNF160; ZNF586; SNAI2; ZNF83; ID3; NPAS2; TLE4; MAF; ZNF512B; FOXF1; AHR; C1QBP; SMAD6; BHLHE41; PSIP1; ZNF91; LOXL2; TCEA1; ZBTB38; DDIT3; SOX9; RNF10; RBPJ; ERG; ID1; MED21; TBL1X; DACH1; NR2F2; HEY1; ZFP36L1; APEX1; IRF8; WWTR1; NFATC3; ATF5; YBX3; HOXC6; PUF60; CRK
Down-regulation 85 SAP30; RXRA; BASP1; MYCBP; HMGB2; LHX1; HIPK3; MED27; CENPF; ABL1; VGLL4; CDYL; EN1; RBL2; KAT2B; MLXIP; RNF6; WT1; POU3F2; ELF5; MAGED1; CTBP2; ERBB4; ATF3; ZIC1; KLF2; RARA; AES; HDAC9; VGLL1; GRHL2; PAX6; FOXI1; SIX2; KLF4; E2F8; TFAP2B; SOHLH2; TP73; MNX1; FOXA1; FOXG1; MYCN; RFX7; SOX5; HMGB3; ASCL1; TOX; NKX2-2; LHX2; CREM; NR5A2; CDX1; CRYM; FOXJ1; LIMD1; ELF4; TOX3; NEUROD1; MYB; POU2AF1; DAXX; GATA6; WDHD1; HOXD11; OLIG2; E2F2; PAX5; ZNF423; TXNIP; HIC2; NKX2-1; WNT4; ZBTB16; SPIB; TBX2; ADRB2; TCFL5; SOX17; GATA3; EGR3; GATA2; IKZF1; RELB; SUV39H1