Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24993	Osimertinib	GSE70138	SKL	Human	24h	0.12uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	45	HOXA5; SATB1; NR2F1; TSC22D2; IRF7; KLF6; ZNF131; TRIM22; STAT1; HOXB5; ZNF160; IRF9; ZNF573; COPS5; HOXB7; ZEB2; HOXB2; RAN; TBX3; FOXD1; BMI1; HSBP1; SP110; CRY1; PSIP1; HOXC10; ID4; MEIS1; ZNF83; ZBTB38; NR2F2; ATF5; ASCL1; TLE4; HMG20B; ZIC1; HOXC6; RBM39; HOXB6; NFATC3; WWTR1; TRIP6; YBX3; PBX1; PUF60
Down-regulation	83	ARNT2; KDM5D; RXRA; MKL2; MYRF; TFAP2A; VGLL4; IRX4; ISL1; FOXI1; ERBB4; TP73; LIN28A; PHOX2A; NKX3-1; KLF11; ATOH1; PHOX2B; NFE2L3; SKIL; BARX1; IRF6; ZNF141; MYT1L; TLX3; ZNF281; MECOM; ZNF835; SIX3; SRY; SOX13; HOXD3; TAF1A; FOXH1; PLAG1; TFCP2L1; TP63; CBX2; BLM; VGLL1; MNX1; EN2; LHX3; HOXD1; DLX4; ZNF257; DLX5; FOXA2; NR3C2; NANOG; KMT2A; ZNF552; ZBTB18; WNT4; GATA3; LHX6; OVOL1; ELK3; ELF4; TFAP2C; HIC2; ZNF227; NR5A2; JUNB; DAXX; ZNF423; GATA6; E2F2; BRIP1; GFI1; SOX17; ZNF124; MYBL2; ZNF331; ZNF711; SSX1; TCFL5; EGR3; GATA2; MYB; SPIB; IKZF1; RELB