Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24990	Osimertinib	GSE70138	SKL	Human	24h	3.33uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	51	SAP18; SUV39H1; PQBP1; AES; HOXA5; ARID4B; ZBTB1; TGFB1I1; SNAI2; SHOX2; NR2C1; ZBED2; SAP30; TSC22D2; JUP; RBPMS; SATB2; PLAGL1; TRIM29; FOXF2; MED21; TRIM22; COPS2; PFDN5; TLE1; HOXB5; TAF9; HOXB7; EYA2; RUNX3; ZNF146; TFEC; CREBL2; THAP11; HOXC10; BHLHE41; INSR; HOXC6; INSM1; STAT1; CITED2; HOXB6; ATF5; IFI16; PITX1; APEX1; MAFB; EHF; HOXB2; ESR1; TRIP6
Down-regulation	66	HES1; MYOG; KLF6; RXRA; CNOT1; MSC; PBRM1; MYF6; SF1; ZFPM2; ZMYND11; KLF2; NFATC3; ZSCAN18; ID3; BATF; NFAT5; ZNF195; MEF2C; CREB3L2; SMARCA1; HIPK2; ENO1; NFE2L3; ERBB4; FOXJ1; ATF3; HMGB3; E2F5; NR4A2; NPAT; ZBTB20; WHSC1; PSIP1; ZSCAN31; PBX3; BLM; MAGED1; PEG3; ZNF331; NKX2-1; TCF7; BACH1; ELF3; ZBTB43; ZNF423; ZNF22; MECOM; CHD7; SPIB; ZBTB16; ASCL1; ZNF551; ZNF586; FOXA2; GATA3; EGR2; GATA2; WT1; YBX3; LEF1; IKZF1; RELB; E2F2; SOX9; TCFL5