Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24989	Osimertinib	GSE70138	SKL	Human	24h	10uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	81	FOSL1; NCOA3; NFKBIA; HMGA2; ETV1; ID2; HMGA1; ZNF589; MAF; TCF21; ADRB2; JAK2; BHLHE40; TSC22D3; ARNTL2; ZZZ3; FOXF1; SP100; IRF9; CIZ1; ZNF24; NPAS2; NKX3-1; SIM2; STAT1; BNC2; HOXB5; YAP1; TRIM22; ARNTL; HBP1; NR2C1; MITF; PFDN5; MDM2; IFI16; NPM1; TBL1X; SALL1; RBPJ; TRIM29; HDAC9; KLF4; SHOX2; PBX3; TLE1; NR2F1; THAP11; SNAI2; CREBL2; TRIM16; CNBP; FOSB; CITED2; ZNF217; ATF5; HOXB2; MNDA; TAF9; PEG3; FOXN3; SP110; HOXB7; MXI1; TRIB3; RBM39; OSR2; COPS2; BHLHE41; ZNF146; FOXD1; TBX3; MAFB; ATF4; TRIP6; HOXB6; HMG20B; YBX3; WWTR1; NFATC3; SOX9
Down-regulation	86	MYCBP; MEF2C; LMCD1; HES1; SAP30; EGR1; RARA; PAWR; KLF10; MAGED1; HIPK3; NFYC; E2F5; NFIC; RRN3; MDM4; EZH2; GABPA; SUB1; WDR77; HMGN3; RXRA; ZNF711; VGLL4; KLF2; TOX; POU4F1; PAX5; NLK; IRX5; ZNF587; TAF9B; ZNF444; ID3; PITX2; TAF4; MYB; DLX2; FLI1; ECD; VDR; CDX2; RUNX1; POU2AF1; JUP; EGR4; SOX11; NCOA1; MSX1; TCF7L2; SOX10; CHD4; ZNF552; AEBP1; PLAGL2; BLM; NKX2-2; MYT1L; SNAI1; LEF1; EGR3; ZEB2; EGR2; HMGB3; ZNF551; TCF4; TCF7; WDHD1; WT1; WNT4; DACH1; ZNF586; MECOM; TXNIP; LOXL2; OLIG2; GATA3; GFI1; IKZF1; ESR1; E2F2; TCFL5; SOX17; SPIB; RELB; SUV39H1