Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24978	Motesanib	GSE70138	SKL	Human	24h	3.33uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	44	PPARG; USP16; CTR9; HMGA1; GATA2; BMI1; SUB1; HEY1; CCNC; SOX4; RELB; TBL1X; MKL2; RORA; TCF25; TRAK1; TGFB1; SFPQ; TBX3; BTF3; ILF2; TGFB1I1; POU2AF1; PSIP1; ID1; BACH2; LOXL2; FOXG1; JUP; DEK; ID3; ID4; TRIM29; BHLHE41; TLE4; HMG20B; COPS2; SNAI2; VGLL4; ASCL1; PBX1; HOXB2; TRIP6; PUF60
Down-regulation	98	MYC; PAWR; PSMC3IP; ZNF136; SMAD5; GATA6; AEBP1; MED23; MBD2; NR0B1; FOXA1; TCEB2; CTBP2; TRIB3; MECP2; TAF1; E2F8; THRA; NFIX; ERBB4; MTA1; MYB; DACH1; PIAS1; NFE2; IRX5; AR; NR4A1; NFATC3; NFYB; NR4A2; TAF1D; TBL1XR1; ZNF264; PAX6; NLK; ERG; SAP30; KDM5D; PHF20; MED1; IRF6; BNC1; ZNF124; BCL11A; CBFA2T3; HDAC4; HIPK2; ZKSCAN1; ATF5; SERTAD2; RFX7; PIAS2; CREBZF; NFX1; TOB1; ZNF22; ZNF586; TTF2; ZNF770; SOX3; PITX2; ELF4; TFEC; MXI1; CRYM; ING3; ETS2; TOPORS; OSR2; MYCN; HLX; KLF13; ZNF75D; WNT4; MEIS1; MECOM; HMGB3; EHF; KLF2; SOX17; FOXA2; KLF9; GATA3; NFE2L3; EMX2; E2F2; NEUROD1; NPAT; ZBTB20; ADRB2; TCFL5; DAXX; MTF2; EGR3; IKZF1; LEF1; SUV39H1