Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24977 Motesanib GSE70138 SKL Human 24h 10uM EID0062
Types Number Response transcription factors
Up-regulation 43 ZFPM2; HMGA1; ZNF302; ID4; SP110; FOXK2; IRF7; MNAT1; SP100; FOXC1; IRF9; CTBP2; STAT1; WWTR1; NPAS2; TAF9; TRIM22; ZSCAN18; PHIP; HIRA; BHLHE41; PSIP1; TAF10; BNC2; PBX1; IFI16; MITF; HHEX; ZIC1; HEY1; CBFB; RBM39; SOX9; IRF8; ATF5; ARNT2; EHF; YBX3; PEG3; TRIP6; PUF60; CRK; NFATC3
Down-regulation 40 RXRA; FOXO1; KDM5D; HOXA1; NRBF2; ELK3; CALR; SMARCA2; AFF1; MED1; WHSC1; LPIN2; CHD1; JUNB; KLF2; CREB3L1; NR3C2; MXD4; RARA; BLM; TOB1; NPAT; LEF1; MECOM; TRIM32; PLAG1; ID3; HIC2; ZBTB16; ZNF586; GATA3; EGR3; E2F2; RELB; FOXA2; PPARG; NR3C1; ELF4; TCFL5; SUV39H1