Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24974 Wz-4002 GSE70138 SKL Human 24h 1.11uM EID0062
Types Number Response transcription factors
Up-regulation 55 GLI2; ZBED2; CNOT2; PKNOX2; PITX1; ZFPM2; GTF2IRD1; ZNF589; FOXO1; NPM1; TAF1D; SNAI2; NR2F1; DDX17; XRCC6; ZNF586; ZNF329; SALL1; FOXL2; TAF9; EHF; SMARCD3; MSX1; ID4; TRIM16; PFDN5; LOXL2; TRIM22; PEG3; FOXD1; ZFP36L1; HHEX; MNT; MAF; DDIT3; ZNF146; APEX1; MAFB; CBFB; SOX11; HOXB6; THAP11; BNC2; ZNF217; TRIM29; ATF5; TRIP6; IRF8; ZBTB18; RBM39; PBX1; NFATC3; PUF60; HEY1; SOX9
Down-regulation 52 ARID1A; AFF1; DNAJC1; KLF6; MKL2; DNMT3B; HDAC9; KLF2; CARHSP1; ZBTB16; CDK2; POU2AF1; TOX; SOX10; AEBP1; HMGB2; MYRF; ZFP36L2; ERG; KLF13; KLF5; NLK; SIX3; BRD2; MYT1L; LYL1; TFDP2; CITED2; GATA2; PLAGL2; ATF3; ARID3B; MYB; BLM; INSR; PSMC3; TAF9B; ELF4; BCL11A; ELF3; CBFA2T3; EMX2; ADRB2; PAX5; OVOL1; MEIS2; IKZF1; ETS2; DAXX; GATA3; E2F2; TCFL5