Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24960 Gsk-1059615 GSE70138 SKL Human 24h 10uM EID0062
Types Number Response transcription factors
Up-regulation 85 SOX4; ZNF692; ZMIZ1; HOXA5; ZNF266; FOXO4; CBFA2T2; EGR1; NCOA3; PHF1; ETV1; SETDB1; PNRC1; ARID4B; HMGA1; HMGA2; HBP1; CALCOCO1; PAXBP1; BRD8; ZNF83; TCF25; DDIT3; RERE; TLE2; ZNF232; JARID2; PCGF2; MED16; KAT2A; BTAF1; TGFB1I1; ZNF432; CIZ1; MAFB; TCEA2; AES; NR2C1; PFDN5; RBM39; CNOT2; FOXG1; PCGF1; BTF3; CBX7; NR1H2; DEK; CREBL2; SHOX2; TGFB1; TCEA1; CITED1; CNBP; COPS2; HDAC1; TRIM22; SATB2; HMGB1; GTF2IRD1; TLE1; LOXL2; TBX3; MNT; CTBP1; PSIP1; RBPJ; MXI1; ZBED2; BHLHE41; FOXD1; ETV5; ATF4; RNF10; TRPS1; HMG20B; ZNF217; SNAI2; ARNT2; ATF5; ZFP36L1; HOXB2; ZNF91; SMAD1; YBX3; MEIS2
Down-regulation 105 JUN; MYCBP; PAWR; ATF6; MEF2C; DACH1; LMCD1; MNAT1; ETS1; KLF6; RNF141; HIPK3; NR4A1; KLF5; SMAD5; WDR77; KLF4; ELF3; HMGB2; GATA6; ATF3; PITX2; FOXJ1; IRX5; TRIM25; NR4A3; NR0B1; ZEB2; SFPQ; FOXC1; RUNX1; SIAH2; NFATC3; TOX3; SOX10; ETS2; ZNF556; SMAD3; ESRRG; ASH2L; YAF2; LEF1; SERTAD2; E2F5; ANKRD1; WHSC1L1; IRF6; MYT1L; MSX1; WWC1; MYB; DLX2; FHL5; TRIM16; SMARCA2; ERBB4; MYCN; EMX2; SOX2; CBFA2T3; MAGED1; ZNF770; ZNF124; ASCL1; TAF9B; ZNF711; ZNF423; MYBL1; KLF2; HEY2; JUNB; ID3; FOXL2; ECD; HMGB3; WT1; EGR3; ZNF586; AEBP1; TRIM32; LIMD1; MEIS1; ZNF516; ADRB2; OVOL1; WNT4; CHD7; NFATC1; GATA3; GFI1; FOXA2; PIR; WDHD1; BRIP1; SOX17; MECOM; OSR2; ELF4; NKX2-2; SPIB; E2F2; ESR1; MTF2; RELB; EGR2