Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24942	Ibrutinib	GSE70138	SKL	Human	24h	0.12uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	48	TBP; SP110; PQBP1; SRCAP; CARHSP1; STAT1; TAF11; IRF9; FOXK2; TRIM22; TFAP2A; ZNF593; THAP4; PRRX1; SP140L; EYA2; ZBED2; ZNF131; ZNF232; ZNF623; SP100; SUMO1; ZNF266; ZNF7; CTBP2; GLI3; TULP3; IFI16; HSBP1; ZFP36L2; STAT4; PFDN5; FOXF2; CD3D; IRF1; BNC2; TFAP2C; NFIB; ARNT2; MEIS2; IRF7; ATF5; EHF; MAFB; SNAI2; PEG3; NFATC3; SOX9
Down-regulation	99	LMCD1; NCOR2; ABL1; USF2; SMAD2; TOX3; BASP1; SSRP1; KLF6; ZNF587; TSC22D3; PATZ1; URI1; ZBTB38; NCOA6; SMARCC2; BCL3; NHLH2; SRF; PAX5; KDM5D; KLF5; BRD2; YWHAB; ZBTB18; UIMC1; RLF; ZNF160; TCF12; NCOA1; ZNF721; TCF7; MAGED1; PHF2; BCLAF1; TFEB; CREB3L1; EZH2; PRKDC; MYRF; CBFA2T3; CHD7; POU4F1; ZNF226; HOXC10; ZNF423; MYT1; ZNF281; TRIM32; NFATC1; CENPF; ZNF264; HOXC6; PBX3; ETS2; HMGB2; INSM1; FOXN3; ASCL1; CUX1; MED1; RARA; BTG1; FOXA2; PLAGL1; FOSB; EN2; AEBP1; KLF2; DDX54; REPIN1; FOXJ1; ING3; MYT1L; HOXB7; TOB1; ZNF586; PLAG1; FOXL2; BLM; NFAT5; GATA6; ELF3; MYB; TOPORS; TLE4; HMGB3; NR1D2; LEF1; ZNF652; GATA3; MEIS1; NKX2-2; SOX17; SPIB; TCFL5; IKZF1; RELB; E2F2