Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24941 Ibrutinib GSE70138 SKL Human 24h 0.37uM EID0062
Types Number Response transcription factors
Up-regulation 31 NR1H2; SPEN; RORA; BNC2; ZNF593; HMGA1; ZNF146; ZZZ3; MAF; ZFP36L1; HOXB7; FOXG1; ETV5; RBPJ; TRIB3; TBL1X; MXI1; IFI16; TRIP6; COPS2; PFDN5; SNAI2; ATF5; MEIS2; MAFB; HMG20B; PBX1; HEY1; WWTR1; NFATC3; PUF60
Down-regulation 79 BASP1; SAP30; MYRF; CTBP2; ERG; PAWR; NLK; PAX6; IRX5; BNC1; DACH1; HMGN3; ZNF721; KLF6; ZNF329; DNMT3B; ZFP36L2; ZSCAN31; ZSCAN18; SMAD3; KMT2A; CBFA2T3; KLF4; SIX3; PBX3; KLF1; DLX4; ZNF165; KAT2B; ETS2; ZBTB20; MYT1L; ZNF711; E2F5; MAGED1; AHR; SNAPC4; ZNF586; SMARCA2; TP63; NFE2L3; TSC22D1; ELK3; SNAI1; TFDP2; NFATC1; TAF5; GATA1; TFAP2C; NKX2-2; TOPORS; KLF9; KLF5; NR4A2; DAXX; OVOL1; KLF2; PSIP1; MED14; DLX5; GATA2; MYB; NPAT; E2F2; GFI1; NANOG; ZSCAN16; NEUROD1; ELF4; MYBL1; IKZF1; OLIG2; GATA3; EGR2; MTF2; RELB; TCFL5; SUV39H1; LEF1