Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24940 Ibrutinib GSE70138 SKL Human 24h 1.11uM EID0062
Types Number Response transcription factors
Up-regulation 36 LMCD1; NFIB; SHOX2; TULP3; CITED1; CHD9; ZFPM2; RBPJ; NPAS2; SMARCD3; HMGA1; PBX3; DDIT3; GTF3A; SMAD1; KDM5A; NR2F1; ZNF146; FLNA; TRIM29; MXI1; IRF8; ATF5; ETV5; APEX1; WWTR1; PFDN5; ATF4; LOXL2; BHLHE41; ZIC1; YBX3; NFATC3; ZFP36L1; MEIS2; CRK
Down-regulation 82 MYCBP; CERS6; FOXJ3; HOXB13; MSX1; HMGN3; AFF1; ZNF611; KLF6; CTNNB1; JUP; PAWR; ZSCAN18; FOSB; RAD21; ZNF721; MYB; ID3; TOB1; SAP30; ING2; CDX1; CALR; ARID3B; KLF4; SIAH2; DNMT3B; BRD2; CREM; TGFB1; ETS2; ZNF587; DACH1; ZNF160; E2F5; ID1; ZNF165; ZNF264; LIN28A; TCF7; FOXA2; KLF10; NR3C2; SIX3; BASP1; MYT1L; ESR1; BCOR; FOXJ1; KLF5; AEBP1; CBFA2T3; OVOL1; KDM5D; NKX2-2; PSIP1; ZNF586; GATA6; IKZF1; HIC2; ZNF711; HOXC6; GATA3; ZBTB16; TOPORS; E2F2; TP63; JUNB; NFE2L3; NFATC1; KLF13; HMGB3; LEF1; ELF4; TXNIP; SSX1; RELB; SOX17; SPIB; GATA2; TCFL5; SUV39H1