Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24934 Kin001-244 GSE70138 SKL Human 24h 1.11uM EID0062
Types Number Response transcription factors
Up-regulation 601 CCNA2; ELF3; BRCA1; FOXO4; USF2; ZNF184; YEATS4; SSBP3; SETDB1; ID4; ZNF107; PBXIP1; NR0B1; ZNF3; ZNF813; TCF21; FOXJ1; BRD2; ZNF200; PPARG; FHL5; ZNF212; BRD4; BARX2; FOXL2; SP2; THAP10; EZH1; MECOM; OVOL2; PIAS1; POU4F1; NR1I3; E2F8; ARNT; LPIN2; TAL1; MZF1; NKX2-1; HMG20A; POU3F1; CRYM; ZNF273; MED12; ZFP64; ZBTB39; EGR4; ZNF639; PRDM4; ZBTB14; ZNF536; HEY2; YWHAB; HLF; POU4F2; RBL1; PKNOX1; CASZ1; ZFP37; HR; MTA2; WWP1; KLF5; PRDM2; IRF1; GRHL2; PRDM1; ZNF174; NR3C1; ZNF180; BRF2; ZNF253; HOXA2; HNF4A; TAF6L; MBD4; ZNF142; ZNF215; NR1H3; TOPORS; IKZF1; TBX4; ARNTL; ZNF423; MED1; ZNF446; CERS4; WDR77; KLF12; DDX54; FOXE1; BCL3; ZNF335; PPP1R13L; HOXB9; LHX6; E4F1; KLF15; MAPK8IP1; POU5F1B; KMT2D; ZNF816; SOHLH2; RBBP5; GFI1; ZSCAN2; IL16; RORC; WDHD1; CIR1; GMEB1; ZNF510; IRF5; POU2F3; IRF4; MED7; RFX2; ZNF764; NR2C2; ZNF408; HOXC5; HIPK2; TBX2; FOXJ2; MED31; ZNF226; KAT2B; ORC2; NSD1; CHAF1B; SUV39H2; NFIX; ZXDC; SUV39H1; NFE2L3; SIAH2; ZNF281; RBPJL; BACH1; NR1H4; USP21; HNF4G; ZNF589; AIRE; ATF6B; PIAS3; TAF5; ZBTB25; WHSC1L1; DNMT3B; ZNF814; SKIL; EVX1; IKZF4; KLF3; RBM14; AFF2; MAK; ZNF205; BRCA2; RFX3; MDM4; EGR2; ZNF45; TRIM25; SSX1; MYT1L; ZSCAN16; KLF6; TCF12; ZNF175; ZNF227; PRDM12; ZNF254; RFX7; ZNF613; HOXA3; SNAPC4; ZFP69B; NHLH1; KDM5A; ID3; ZNF235; INSR; ZNF443; ZNF211; EP400; TBX21; ZNF391; SNAI1; NPAS1; PRDM5; ZSCAN32; ARID3B; BCL11B; MAML3; NKX6-1; TAF1A; MYB; RFC1; TBL1XR1; BRIP1; SOX3; SIX5; TTF2; BLM; ZKSCAN4; POU6F1; SCAI; ZNF432; ESRRB; THAP1; LHX2; KLF13; CBX7; ZNF614; ZNF14; THAP9; GATA4; HOXC11; EN2; NEUROD2; ZNF165; PML; ZNF324; POU3F4; BCOR; BRPF1; ZNF682; TCF4; NEUROG1; TAF4; PRDM14; ZNF492; NR6A1; ZNF225; ONECUT1; ZNF695; HEYL; DOT1L; ZNF329; ZNF528; ONECUT2; ZNF440; PRDM9; MYCL; MTF2; SOX30; UBTF; E2F1; ZNF22; PITX3; PHOX2B; HIVEP1; ZNF236; SIX3; ZNF557; ZNF10; FOXN1; TAF1C; HABP4; ZNF675; ZNF550; RARG; ZNF287; OVOL1; ZBTB3; RELB; ZSCAN5A; ZNF23; TCFL5; ZNF221; NRF1; NR5A1; DMRT1; NR1I2; TGS1; ACTL6B; ASCL3; SP4; TP63; GABPA; HOXA7; NR1H2; CDX4; ZNF79; TULP2; ZNF556; CEBPZ; NPAT; ZNF112; ZBTB7C; HDAC11; ZNF768; ZNF654; SIX6; IKZF2; KMT5A; ING1; HOXC13; ZNF8; PRDM13; ZNF248; THAP7; ZBTB44; EHMT1; MAFK; TADA2A; HDAC7; DLX6; ZNF783; CBL; KLF10; HOXC4; TFAP2B; CSDC2; ZNF154; NR5A2; MAP3K10; TBL1Y; ZNF671; PROP1; POLR3C; RXRG; THRA; ZNF214; ZNF134; PEX2; NR2E1; KDM4A; URI1; YAF2; IKZF3; STAT6; ZIC4; ING2; ZNF507; ZNF282; TRIM32; NKX2-8; KDM4C; CIITA; SOX17; ZNF442; WNT4; ZNF835; EP300; TCF7; GATA2; ADRB2; RUNX2; ZNF770; LZTS1; CBX2; JUNB; NOCT; TAF7L; FOXD2; ID1; ZNF157; LMO1; KLF2; ZNF222; PAX4; SOX5; SRY; FOXD3; SSX7; PITX2; NRBF2; ALX4; SMARCA2; ZNF701; PRDM8; ZNF419; ZBTB48; ZFP2; ZNF580; MED25; ZNF407; KLF8; POU6F2; NEUROD4; ZNF148; CUX2; PAX3; ETV3; ZBTB6; FOXE3; GBX1; KLF1; PAX7; ASH1L; FEZF2; GCM1; MYBL1; RORB; DCC; LIMD1; ZNF75D; PRDM16; CHD2; ZNF506; ZNF552; CREB1; FOSB; PLAG1; POU4F3; SMARCB1; ASCL2; CCNE1; ZNF551; SKI; ZNF41; MYEF2; GCM2; ZNF787; ERG; PIR; GATA1; HOXB8; THAP3; BATF; KLF7; ZIM2; VGLL1; TLX3; HOXD13; MSC; MNAT1; ETS2; HIVEP3; HES2; MLLT1; NFX1; CAMTA1; TFDP3; SOX21; ZNF473; HOXB1; CAMTA2; ZNF516; EBF2; HAND2; ZNF80; ING3; TUB; POU2F1; TP73; NFYB; ZNF749; HDAC1; ZNF234; ERCC2; SSBP2; ZNF286A; ZNF257; ZNF81; VENTX; POU3F3; MYRF; IRF2; SFMBT1; ZNF334; E2F5; ZNF141; SSX3; GSC2; NEUROG2; ARID4A; SIM2; NFKB1; MXD3; TRIM24; THRB; SOX11; SMAD6; ZNF674; TEF; CREB3L2; ZNF696; DLX4; TSC22D4; RNF141; ERBB4; TFDP2; ZNF780B; ZNF710; ZNF343; LHX3; CARF; ZNF223; VHL; HOXA1; MED15; NEUROG3; TAF4B; FOXM1; TOX; AFF1; MSX2; MBD1; ZMIZ2; SCRT1; RFX1; HNF1B; UTF1; ZNF444; PRDM10; HIVEP2; KDM5D; ZNF135; TONSL; MED14; GFI1B; TAF9B; ZNF350; AEBP1; LMX1B; ZNF471; IFNB1; ZNF667; ZNF493; HNF1A; TLX2; NKX2-5; NRL; EMX1; PAX1; ZNF324B; ZNF771; HDAC5; ATF3; ANKRD1; ZNF124; TFAP4; KMT2A; POU1F1; ZFHX3; HESX1; CBFA2T3; ZBTB43; HMGB3; FOXH1; SOX18; SOX13; PSMC3; ZNF304; ZNF711; TOB1; ZBTB24; DAXX; SAP130; BRWD1; CREBZF; POU2F2; SHOX; BNC1; ZNF778; FOXA2; AHR; NEUROD1; ELF4; TCF20; STAT4; PHOX2A; LEF1; MXD4; NR3C2; ZNF217; OLIG2; PIAS2; SPIB; NFRKB; NKX2-2; VDR; E2F2; BAZ2A; TFEC; SOX2; CDX1; CD3D; DLX5; RUNX3; PGR; NFATC1; HOXD11; NR2F1; ETV5; POU2AF1; TFAP2C; ZEB2; ZBTB16; TXNIP; NFATC3; NANOG; REPIN1; ESR1; HOXD1; HIC2; ZNF586
Down-regulation 152 BHLHE40; DDX17; CTBP2; RNF138; MEOX1; MITF; PBX1; RBFOX2; DRAP1; SIM1; XRCC6; RBBP8; RNF4; TRPS1; TSG101; CEBPD; HLTF; HHEX; HEY1; YBX1; PBX3; TAF10; HIF1A; STAT1; SNAI2; C1QBP; SOX9; GTF2IRD1; ASCL1; HMG20B; TGFB1I1; MAF; NPAS2; DEAF1; CCNC; ZFHX4; ZKSCAN1; FLNA; IRF8; CEBPB; CBX3; CDC5L; FOXK2; TRIP6; CTBP1; TRIM29; BTF3; HSBP1; PDLIM1; PTTG1; NR2C1; HOXB2; SHOX2; APEX1; TRIM22; MED24; PPRC1; GTF2F1; PHF1; CBFB; BAZ2B; ZBED2; ZNF652; MAFB; CITED1; SUB1; TGIF2; RCOR3; CITED2; PCGF2; NPM1; HIPK3; SUPT7L; HDAC2; ERCC3; SIX2; SP110; BRD7; SUPT4H1; SUMO1; NR2F2; YBX3; LITAF; BNC2; SMAD1; SMARCD3; IRF7; HTATIP2; THAP11; BCL10; ZNF91; PTRF; VPS72; MEIS2; RFX5; TAF1D; PCGF1; EWSR1; ZNF146; SLC2A4RG; RBPJ; PUF60; PITX1; MNT; TCF7L1; HBP1; COPS5; MNDA; CSDE1; SIX1; PEG3; NRIP1; HMGN3; TRIM16; NONO; ZNF43; BACH2; CRK; TULP3; TLE1; DLX2; TRAK1; RBM39; ZNF83; MTDH; CREBL2; NFE2L1; CNBP; RNF10; TAF9; IRF9; TRIB3; MYCN; TFEB; MEIS1; IRX5; ZFP36L1; ATF5; FOXF1; DDIT3; ATF1; ZNF593; HOXB6; ELF5; WWTR1; EHF; ATF4; PFDN5; COPS2; EMX2; GTF3A; TLE4