Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24915 Bosutinib GSE70138 SKL Human 24h 0.04uM EID0062
Types Number Response transcription factors
Up-regulation 74 GLI2; MED17; LITAF; KAT2A; ZNF692; HMGN3; PBX3; TOX3; KLF6; CBX5; SUZ12; TAF7; FUBP1; SERTAD2; RNF138; LMCD1; CTBP1; ZNF665; ZNF652; ZNF430; ZNF467; CEBPG; AES; HMGB2; MLXIP; ZNF91; CREB3L2; HHEX; LOXL2; MNDA; TFEC; BATF; SAP30; AATF; CREB3L1; ST18; TCF21; SOX9; DMTF1; POU2AF1; ZBED2; RBM39; MYRF; CTBP2; EYA1; MED21; ZNF580; TRIM16; SMAD7; MYCN; ELF1; BNC2; TRIM29; JUP; PDLIM1; ASCL1; TLE4; SIX2; FOXD1; MED24; COPS2; NR2F1; SNAI2; HOXB6; EHF; ZKSCAN1; ATF5; ETS2; MEIS2; NR2F2; HEY1; IKZF1; PUF60; CRK
Down-regulation 91 CNOT6; ZNF468; MAZ; MEOX2; FOXG1; SKI; TDP2; MLXIPL; SMARCA1; MEF2C; MSX1; NFAT5; CBX6; TMF1; ELF3; EGR3; PAX9; MEF2D; NEUROD6; BCL11B; FOXC1; JARID2; ZNF623; KLF10; HMGA1; ZNF184; NRBF2; ZSCAN32; PRKDC; MAML1; CCNT1; FOS; CEBPD; ZIC1; LHX6; HOXD13; ZNF189; ESR1; OSR2; SREBF1; SMAD3; ACTL6A; HOXD10; EYA2; NKX2-2; BRWD1; HIVEP2; ZNF350; NLK; TBX1; ZBTB25; FOXA1; NFE2L3; HOXA1; HOXD11; MNX1; TAL1; TFAP2C; ZEB1; ZSCAN16; TRPS1; ZNF764; ZBTB43; ZNF222; ZBTB16; SOX17; TCF7; TRIM32; BLM; KDM5A; DLX5; ATF3; DAXX; EMX2; WNT4; ZNF75D; EGR2; ADRB2; ZNF217; NFATC3; ZNF124; E2F2; YBX3; GATA3; TCFL5; BHLHE41; OLIG2; TXNIP; WWTR1; ZNF423; LEF1