Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24914	Bosutinib	GSE70138	SKL	Human	24h	0.12uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	118	JAK2; MKL2; PKNOX2; SLC2A4RG; HOXA5; CREB1; ARID1A; NUP62; IRF9; MLXIP; IRF7; CREB3L2; GMNN; TSG101; MTA1; ZNF500; ZSCAN18; TAF6; TOX4; MED25; SUPT5H; KAT2B; KAT2A; ARID5B; HOXB2; TBX2; PRPF6; IRF3; STAT1; WIZ; NCOA1; ZNF688; TCFL5; SATB2; NR1H2; TRIM28; ZNF264; MNDA; FOSB; FOS; MSX1; KLF11; TCF21; HHEX; WT1; PEG3; LMCD1; TFAP2A; ARNTL2; RNF138; ZNF467; ZNF589; ZNF652; CDC5L; ARNT2; HOXB5; AHR; NELFB; MXI1; GCFC2; CITED2; SOHLH2; HTATIP2; ZNF512B; MYCN; ZNF444; JUP; ID4; KLF7; ZNF217; PARP1; ZMYM2; E2F8; SHOX2; GTF2IRD1; HLX; PDLIM1; CTBP1; JUNB; ZNF91; INSR; IRF1; SMAD6; PBX3; ZKSCAN1; ERBB4; MAFB; VDR; HIPK1; FOXD1; ZEB2; ETV5; MYCL; PITX1; GTF3A; ATF7IP; TBL1XR1; THAP11; ID3; HLTF; IRF6; IRF2; ZNF331; SMAD1; HEY1; HOXB6; SMARCD3; BTG1; ATF5; REPIN1; SNAI2; ZNF423; TRIP6; IKZF1; PUF60; PBX1; NFATC3; LEF1
Down-regulation	149	CDK7; SOX4; ERBB2; DDX5; ABL1; SMARCA1; DDX17; MYRF; MEF2A; DACH1; HOXC10; BASP1; FOXJ3; TCEB2; ZMIZ1; RBPMS; TCF12; TSC22D3; CREB5; SCAND1; HOXB13; TLE1; NRIP1; EPAS1; CTBP2; BIRC2; TSC22D2; GON4L; KDM5B; CDYL; ARID4B; NR4A3; TOB1; PMF1; TOX; MED6; TOX3; NKX3-1; CCDC59; GTF2I; ZNF23; ZNF536; NCOR2; SKIL; ZBED4; GATAD2A; TGFB1I1; TRIM16; AIP; ZKSCAN7; NRBF2; MITF; RBPJ; HOXC6; RCOR1; RBBP5; CRK; UBE2L3; TAF11; THAP1; JARID2; EGR2; SETD2; BRPF1; CITED1; TBL1X; ZBTB38; ZNF189; NKX3-2; RBM14; HOXB9; ZNF302; HDAC9; MAX; MEF2C; EDF1; SAP30; RUNX3; CREM; ZFHX4; KLF4; MNT; TCF7L1; PURA; PIAS3; TERF1; UBP1; COPS2; NLK; DLX2; NAB1; PHF20; NR3C2; NR2F1; ANKRD1; YBX1; ORC2; GCM1; BRD2; BRIP1; ESR1; TSC22D4; ZNF593; HMGN3; ARID4A; TXNIP; MBD2; HSBP1; PML; PTRF; HOXD10; SMAD7; PCGF2; SKI; PLAG1; ZNF516; CBFB; WDHD1; TAF9; TBX3; LIMD1; TWIST1; HOXD1; ZNF227; CREB3L1; ID1; ZNF10; EMX2; BHLHE41; ATF4; E2F3; ELK3; KDM5D; NFATC1; NR2F2; ETS2; TOPORS; MED14; ZSCAN16; TSC22D1; ADRB2; E2F2; STAT4; GATA3; SOX9; TLE4; NKX2-2; GATA2; SUV39H1