Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24908 Bix-02189 GSE70138 SKL Human 24h 0.12uM EID0062
Types Number Response transcription factors
Up-regulation 46 SATB1; ZNF131; POU4F1; MMS19; CITED1; HSBP1; HMGB1; NPM1; BASP1; TCF4; SMAD1; LOXL2; DEK; UBE2I; PAX5; NFIB; APEX1; PFDN5; ZBED2; TFEC; TAF9; RBM39; ZEB1; PTRF; BNC2; CBFB; MAF; TRIM29; THAP11; BTG1; GTF3A; EMX2; NFATC3; IRF8; ID4; SNAI2; HOXC6; BHLHE41; HEY1; YBX3; SOX9; ATF5; HOXB2; ESR1; HOXB6; PUF60
Down-regulation 60 KDM5D; RUNX3; RXRA; TTF1; HMGN3; AHR; MECP2; ZNF134; MYRF; AFF1; IRF4; PLAGL2; SOX10; CTNNB1; HSF2; PBX3; WHSC1; ZBTB16; TRIM24; FOSL2; LIN28A; SIAH2; CREM; TOX; MAGED1; NR4A2; BLM; RARA; PLAGL1; HIC2; SSX1; LPIN2; BRD2; ZNF211; SOX13; GATA3; ZBTB43; MYT1L; ZNF165; HLF; KLF2; FOXA2; REPIN1; HMGB3; ZNF586; ZNF551; ZNF331; ELF4; EGR3; MEIS1; NKX2-2; MECOM; LEF1; SOX17; ADRB2; E2F2; TCFL5; RELB; MYB; SUV39H1