Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24906 Bix-02189 GSE70138 SKL Human 24h 10uM EID0062
Types Number Response transcription factors
Up-regulation 56 SMAD4; SREBF1; TFAP2A; VPS72; LITAF; HOXA10; CBFA2T2; PAXBP1; KLF11; ST18; ZNF232; NAB1; PURA; ZNF665; ZBTB1; NPM1; BTF3; PQBP1; CEBPD; GRHL2; DDIT3; ZNF611; PSIP1; RBBP8; PHF20; CREBL2; NFATC4; MITF; BHLHE41; TCEA2; EHF; ATF5; WWC1; DEK; TRIB3; BNC2; PHIP; MNT; IRF6; ZNF83; TCEA1; CD3D; RUNX3; TRIM22; CREG1; APEX1; HLTF; TOX; ARNT2; PFDN5; PBX1; TRIM29; ZNF652; MAF; NFATC3; ZNF91
Down-regulation 73 ETV1; EGR1; LMCD1; HMGA2; KLF2; SUB1; MDM4; PSMC3IP; YWHAB; MYCBP; MEF2C; NR0B1; ZBTB18; SIAH2; ASCL1; KLF10; RBM14; CHD7; GATAD2A; CREB3L1; FOSB; LEF1; NR2F1; PRRX1; KDM5D; RBBP5; DLX2; ZEB1; ZNF226; TOX3; RFX7; FOSL2; UBE2I; MSX1; TWIST1; NLK; E2F5; POU2AF1; ATF7IP; SOX5; CRY1; ZEB2; BTG1; ZNF423; EGR3; ANKRD1; ELK3; BRD2; PAX5; BASP1; MYT1L; BACH1; ERBB4; MXD4; ZNF551; ZNF586; ADRB2; SOX9; GATA3; EGR2; HLF; RELB; E2F2; MTF2; IKZF1; FOXA2; MYBL1; OLIG2; MYB; GATA2; SOX17; SUV39H1; TCFL5