Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24886	Mitoxantrone	GSE70138	SKL	Human	24h	10uM	EID0062

Response Information :

Types	Number	Response transcription factors
Up-regulation	172	TFAP2A; TCF21; HMGA1; NFKB2; VPS72; ST18; FOXM1; PAX6; JUP; CNOT3; TGFB1; BRCA1; HDAC9; HOXB5; SPDEF; SUPT5H; NFKBIB; CDK2; GRHL2; ATN1; CEBPZ; CCNH; HAND1; MNDA; EED; SRCAP; ZIC3; LIN28A; LITAF; PNRC1; CUX2; ZNF85; DLX2; KAT6B; KLF11; NFIX; POLR3C; AR; NFATC4; IRF6; ZBTB17; MAZ; TWIST1; EHMT2; FOXF1; GMNN; PDLIM1; TLE2; MYBBP1A; SHOX2; GFI1B; ACTL6A; SOX2; PTTG1; SSBP3; MYRF; ZNF74; NOC2L; WWC1; VDR; CDIP1; NKX3-2; CBFA2T2; CREB3; ZNF350; ZBED2; ZNF532; MECOM; VENTX; FOS; TCEA1; FOXF2; KDM4C; ISL1; DNMT1; CALCOCO1; IRF8; MKL1; BHLHE41; IRF1; CBX6; HOXB6; ZNF195; ZNF467; BRD4; FEZF2; JAK2; SNAI2; MEIS2; CCNE1; CIITA; BACH2; CNBP; MED25; GCFC2; ZNF239; BARX1; PRDM12; PRDM14; ARNT2; MEIS1; NFE2L3; HIRA; THAP7; ZNF816; MYBL1; OVOL2; HOXD9; ACTL6B; IRX4; SPI1; BNC2; PFDN5; MYCL; TRIB3; DLX5; CIZ1; FOXI1; MED15; ZNF43; CDX1; BNC1; CEBPG; TFAP2C; BCL11A; FOSB; FOXG1; KDM5C; ZNF528; HIPK2; TCEA2; TBX1; SOX11; DMTF1; RAD21; NR1H2; KLF1; PEG3; CALR; NR2F1; AES; WT1; MYCN; TFDP2; ZNF580; VGLL1; CREBL2; SOX3; SALL1; ZNF589; TTF2; TAL1; PSMC3; MYBL2; SOHLH2; HOXB2; TFCP2L1; ZNF835; KLF13; EHF; ATF3; HHEX; TRIM29; LOXL2; TLE4; HIC2; NANOG; JUNB; PBX1; ZNF91; MAFB; FOXA2
Down-regulation	154	FOXJ3; CDK7; NUP62; ABL1; FOXO4; MAGED1; HOXA5; MYC; ARID4B; IKBKAP; NFKBIA; HOXA10; TSC22D3; USP22; STAT6; PRRX1; BHLHE40; BRD8; KLF6; ZMYND8; SOX4; KLF2; CHD9; IRX5; JARID2; SAP18; BIRC2; TCF12; SPEN; SIX1; NFE2L1; TSC22D1; KAT6A; NKX3-1; HMBOX1; TGIF1; DNAJC1; FOXO3; VEZF1; BRPF1; BRD3; MNAT1; ZBTB18; FOSL1; SIRT2; MED1; CNOT1; SMARCE1; AHR; MAFG; HMGN3; NCOA4; PHF2; ZMYM2; MSX1; MEF2C; RUNX1; NRBF2; MYOG; PBRM1; PURA; XBP1; NFKB1; NCOA1; ZBTB1; RBBP4; DDX5; MYF6; NCOR2; AFF1; ERBB2; BATF; HOXC10; SMAD2; UBE2B; FOXC1; CRY1; NR2F2; TRIM32; ZNF148; POU3F1; ZMYND11; KDM5D; HSF2; BAZ1A; RBM14; ZBTB20; ZNF160; SATB1; ARID4A; HOXC6; ZNF189; MEF2A; NRIP1; ASH2L; SOX10; BMI1; WHSC1; RNF141; BLM; CHD4; ZHX2; TSC22D4; HOXA7; TCF7; SIAH2; ZNF22; ZNF32; REPIN1; SERTAD2; BATF3; CTBP2; RARA; NR1D2; BAZ2B; ECD; ATF1; MSC; CHD1; NR1H3; SMAD3; IL16; TOB1; HMG20A; ZNF721; EGR3; HIVEP2; NFAT5; BCL10; PITX2; SSBP2; BASP1; TULP4; WWTR1; ZNF587; WWP1; KLF10; GFI1; NFATC3; ELK3; ZEB2; NFATC1; ASCL1; CUX1; CHD7; KLF9; NR3C1; HMGB3; HLF; ADRB2; SPIB; TCFL5; ZNF586; RELB