Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24867 Idelalisib GSE70138 SKL Human 24h 0.12uM EID0061
Types Number Response transcription factors
Up-regulation 89 ZNF586; EZH2; ZNF134; ZNF551; ZNF211; MZF1; HTATIP2; SIM2; ZNF544; RHOA; PCBD1; CUX1; BHLHE40; BATF3; NR4A1; ZNF8; BAZ1B; IRF7; CREB3L1; RUVBL2; RBM14; MYB; ARNTL2; RNF10; ZNF444; TFEC; ABL1; MED24; ARID4A; ZNF146; NCOR2; MNAT1; ZNF587; AEBP1; CREG1; SIAH2; MED13; IRF9; MED21; ZSCAN18; PREB; IRF3; STAT4; IRF8; IKBKAP; HOXB6; PURA; TRIM28; NFATC3; JARID2; MYCN; ZNF264; ETS2; RBPJ; BMI1; FOXA2; ARID1A; HOXB5; NPAS2; TOX3; ZEB1; ZNF83; LMCD1; MSX1; HMG20B; GRHL2; RUNX1; LEF1; MITF; CCNE1; ZBED1; TSC22D1; MYCL; CREB1; TXNIP; ZMYM2; ELF5; TCF4; PIR; HOXA5; ZNF217; BCL3; NFE2; ZKSCAN1; ZBTB38; KDM5D; STAT1; VGLL4; SATB2
Down-regulation 138 TFDP1; PHF20; PPARGC1A; RXRG; NR3C2; USP22; TSC22D3; ENY2; BCL10; ZNF623; TFAP2B; NR1I2; PITX2; ARNT2; TCEA1; NR5A2; ZNF654; MYBL2; ZNF232; BRCA2; PRPF6; UBE3A; PEX14; TERF1; ZNF257; ZNF32; ELF1; EPAS1; CEBPD; ZNF492; RNF138; ZNF22; HOXD13; BNC1; C1QBP; CHD4; MYT1L; TGIF2; ZFHX4; PHOX2A; SMAD6; TOX; ZNF529; HMGA1; SIX3; ZFPM2; PRMT2; DNMT3B; PNRC1; NEUROG2; SUPT6H; TCF7L1; FEZF2; HSF1; BHLHE41; CAMTA1; HAND1; TWIST1; NR1H4; ADNP; ZKSCAN4; THRAP3; PHOX2B; HLF; SAP30; ZHX2; ISL1; TBX1; NFATC4; BTF3; LIN28A; ZNF189; SMARCA1; ZEB2; MEIS2; LOXL2; YBX1; RBBP4; ZNF354A; ZNF512B; HMGB2; LPIN2; AHR; AGO2; BACH2; PRDM2; GATA6; SREBF1; RORA; TCF21; DDIT3; SMARCD3; ZBTB16; ZFP36L2; HEY2; SNAI2; BIRC2; ZNF281; TAF9B; RSF1; SALL2; ZNF589; TDP2; PITX1; ZNF423; CTNNB1; FOSB; SMAD2; NKX2-1; SOX10; LITAF; ID3; PQBP1; MYRF; SOX11; SOHLH2; RBBP8; FOXF2; ID1; SOX9; NR2F6; GMNN; TRIM29; NR4A2; NANOG; EGR2; DAXX; MYBL1; TRPS1; ZBED2; ERBB4; FOXG1; PSIP1; ZNF165; MAFB; PEG3; DACH1; GATA3