Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24866 Idelalisib GSE70138 SKL Human 24h 0.37uM EID0061
Types Number Response transcription factors
Up-regulation 62 SATB1; EZH2; PPARG; HTATIP2; BHLHE40; SIX1; ZNF83; CTR9; AFF1; STAT5A; ABL1; EGR1; GTF2IRD1; SMARCA1; IRF4; PURA; ZNF226; TRIM28; ZBTB38; ING3; SMAD7; SPEN; CHD9; SIX2; ZBTB20; CBX5; ALX1; IKBKAP; REPIN1; EDF1; BATF3; CHD7; CREB3L2; TADA3; BMI1; ZNF160; TLE2; MED1; HOXA5; ZMYM2; TRIP6; HLTF; NFATC1; STAT1; NR1D2; WWTR1; CITED2; SOX11; PIR; SATB2; ELK3; ZKSCAN1; TBL1X; CREB1; HMGN3; FOXD1; ZIC1; MAGED1; HMG20B; VGLL4; HOXC6; MAFB
Down-regulation 106 ARNT2; TFDP1; TFAP2C; FOXJ2; TULP3; TEAD4; SMAD1; ATN1; MXD1; BNC1; ZNF654; ZNF749; WT1; MYRF; PEX2; TGIF2; EMX2; IRX4; ZNF232; PQBP1; KLF3; FOXM1; SUPT6H; SOX17; ZNF257; TOX; PHF20; ZFP36L2; CTBP2; ZNF345; BRWD1; RNF138; NR1H4; SPIB; GMNN; TERF2; TFDP2; PSMC3IP; ZHX2; SP140L; TAF1A; HLF; TFAP2A; PSMC3; ZFHX3; HMGA1; TTF2; ZNF623; TCEA1; BHLHE41; ZNF195; TERF1; NFE2; ZNF557; NR5A2; KLF4; LIN28A; TAF9B; ESR1; CERS4; OSR2; E2F8; ELF4; TP63; APEX1; PAWR; EHF; KLF13; ZNF165; IRF6; HAND1; GATA6; PHOX2B; FOXF2; TCF21; YBX3; DLX5; FOXG1; TSC22D1; MYCN; SIX3; CBFA2T3; GRHL2; NEUROD1; INSR; WWC1; ZIC3; NANOG; ISL1; FOXF1; DAXX; ZSCAN31; PBX1; MEIS1; SNAI2; ETS2; TDP2; MECOM; HIC2; HOXD1; NR2F1; RBBP8; ELF3; ERBB4; MYBL1; GATA3