Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24865	Idelalisib	GSE70138	SKL	Human	24h	1.11uM	EID0061

Response Information :

Types	Number	Response transcription factors
Up-regulation	196	EZH2; PARP1; BAZ1B; EN2; KAT5; SIN3B; RHOA; TAF6; ZNF444; NKX3-2; PBX2; TRRAP; JARID2; TFEC; AFF1; GRHL2; STAT1; EGR3; ZNF629; HOXC10; CHD3; E4F1; IRF7; MBD4; PCBD1; RERE; SMARCA4; SCMH1; FOXI1; ATF7IP; IRF9; MED24; SSX1; TAF4; SIX2; IRF3; KDM2A; MTA1; ELF2; RELA; NKX2-1; ZNF212; CUX1; REST; DLX5; SMARCD1; AR; EGR4; SSBP3; TRIM28; PAX8; MAPK8IP1; TAF7L; SIX6; TFAP2C; PITX1; HLF; NR2E1; SP110; BRIP1; POU2F3; DBP; ZNF580; PBXIP1; CD3D; ZNF76; THAP11; IKBKAP; ZMIZ2; CIC; CREG1; ZBTB48; KMT2A; HDGF; TRIM32; TRIP6; SLC2A4RG; GLI3; PGR; CAMTA2; TBL1X; NFX1; NLK; NR3C2; PIAS3; ZBTB24; MDM4; SETD2; DMTF1; HOXA10; PLAG1; RBM14; CHD8; FOXA2; KAT8; BHLHE40; MEN1; NAB2; NCOR2; SCAI; ZNF688; RNF10; EYA2; FOXJ1; SERTAD2; UBP1; CBX4; ZNF394; DNAJC2; STAT6; POLR2A; SIAH2; ZNF692; SPDEF; HOXD10; NEDD8; PLAGL2; SOX12; SPEN; FOXE1; CIZ1; SALL1; FEZF2; LEF1; RFX5; REPIN1; ZNF528; PROX1; NR5A2; PAX9; HOXD11; MKL2; ZNF512B; CTR9; ZNF516; NKX3-1; SIM1; NFIL3; HDAC5; WT1; ZNF468; BRD4; ELF5; ESR1; BATF3; ARID1A; MLXIP; ZNF107; CARM1; CRYM; SOX17; BCL11B; ZSCAN31; ZNF239; RSF1; FOXG1; TFCP2L1; SATB2; CUX2; ZNF83; GATA4; MYCL; ZNF467; KAT7; MYB; TWIST1; SOX9; SIX1; HOXB13; HMG20B; MECOM; RUNX3; NFATC4; PLAGL1; POU4F1; NFE2; HLTF; TLE2; ZNF131; IFI16; EMX2; BCL11A; SMARCA1; FLNA; HOXC6; NKX2-2; SMAD7; MEIS1; PSIP1; MAF; KDM5D; BCL3; VGLL4; MSX1; ID4; MEIS2
Down-regulation	142	TFDP1; LOXL2; NPM1; RB1; CSDE1; DR1; TOB1; CDYL; USP22; NFE2L1; YWHAB; ID3; PTRF; BTF3; CEBPD; DACH1; PRRX1; BBX; C1QBP; TAF9; SMAD4; TRIM29; KLF5; ASH2L; SMAD6; ARNT2; TCEA1; CARHSP1; ZNF91; CCNH; TAF7; APEX1; SOX10; SNW1; ZNF652; SFPQ; ZNF562; CBX3; ZHX2; ZNF536; ZNF423; RAN; ZNF426; TCF3; TERF2; ARID4B; MED6; TLE1; GABPA; ZBTB38; PSMC3; ZBTB18; NONO; TXNIP; ETS1; RNF4; ZFHX4; RBBP4; EPAS1; HNRNPD; ZNF140; STAT3; NR1D2; CHD1; ZNF302; NR2F6; ZEB1; KLF9; ZNF93; TP53; TLE4; ZBTB1; FOXN3; PURA; SCAND1; LIMD1; ZNF232; MED17; ID1; PHF20; TGIF2; NR1I2; TDP2; SAP18; HIVEP2; CCNC; CNBP; SNAI2; TGIF1; FOXF2; ERG; MYRF; XBP1; CBFB; RYBP; ZNF43; KLF2; BIRC2; ZEB2; KLF11; MYCBP; MAFF; CTBP2; BASP1; MNAT1; CHD7; TBX3; TSG101; PBX1; FOXO1; ATF3; POU2AF1; CDK8; RUNX1; ELK3; ZIC1; LITAF; TCF7L2; AHR; TFAP2A; LIN28A; ZNF264; TSC22D2; PBX3; BHLHE41; GATA6; ZFP36L2; PAX5; MXI1; ZBTB16; NR2F1; NANOG; PQBP1; MAFB; ZFPM2; GLI2; HEY1; ZNF165; INSM1; HIC2; TOX; HIRA