Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24864	Idelalisib	GSE70138	SKL	Human	24h	3.33uM	EID0061

Response Information :

Types	Number	Response transcription factors
Up-regulation	153	CEBPA; EZH2; BRCA1; FOSL1; ITGB3BP; PARP1; RUVBL2; ZNF337; KAT2A; MYC; ETV1; EGR1; PCBD1; TRIM27; EED; PLAGL1; CHD8; SIN3B; ERCC3; TLE2; MNAT1; JARID2; AR; PITX1; CDK7; PLAG1; ZNF3; HOXA11; IRF3; ZNF274; SMARCA4; SIAH2; BAZ1B; RBM14; MBD4; FOSL2; SIX1; RHOA; FOXI1; TFAP2C; TRRAP; MTA1; ZNF692; NR4A1; MXD4; GON4L; HMGA2; TLE1; HDAC3; NKX3-1; ARID5A; NEDD8; SSX1; AIP; ZNF282; ABL1; SIX2; PPP1R13L; STAT5B; NR3C2; ZNF710; SPDEF; TRIM32; IKBKAP; HLF; RING1; ZNF146; RCOR1; SOX9; HOXD9; IRF2; PRDM1; HOXA10; FOXA1; ZNF266; BCL6; ELF3; SFMBT1; ST18; THAP10; NKX2-1; TRIM28; NEUROD1; ZNF107; TCEB2; TRIP6; SALL1; HOXB2; PTTG1; ELK3; JUP; BATF3; BAZ1A; HOXD10; FOXF1; BRIP1; DMTF1; SOX17; ENO1; DNAJC2; HLX; LHX6; ESR1; CBX4; ZMIZ2; HOXD11; GTF2IRD1; SP3; PLAGL2; PAX9; RBPMS; GRHL2; ELF5; FOXD1; ZMYND8; KDM5D; HHEX; HMG20B; TFEC; NR2F2; ZBED2; MECOM; ZNF557; CNOT3; ARID1A; SATB2; VDR; ZNF467; SHOX2; IRF4; PCGF2; PAX6; SMARCD3; IFI16; FOSB; ZNF239; HMGA1; TSC22D1; LEF1; BCL3; SOX13; IRF8; ZSCAN31; EHF; FOXG1; TRIM16; MSX1; VGLL4; MEIS1; MYB; ERBB4; SOX11; IKZF1
Down-regulation	132	TFDP1; RB1; SATB1; ARL2BP; FOXO1; ATF4; ZNF24; NFE2L1; THAP11; ID3; TGIF2; SMAD2; SMAD4; NR1D2; ZNF264; ZBTB18; CSDE1; MEF2C; HDGF; NFATC4; ZHX2; PEX2; RNF138; CEBPG; HNRNPD; USP22; KLF3; KLF5; EPAS1; ERG; ARID4B; ZFP64; RXRG; CNBP; ZSCAN18; HMBOX1; CBFB; VPS72; PRRX1; ZNF652; ZNF184; ARNT2; SIRT2; ZNF124; NR2F6; PHF20; TDP2; TSC22D3; BRD3; TERF2; MTDH; STAT1; PKNOX2; ZFP36L2; SREBF2; PBRM1; ZEB2; TMF1; ZBTB43; SMAD1; TCF15; ARID5B; ZNF281; PHF1; BHLHE41; SNAI2; PITX2; DDIT3; YWHAB; BIRC2; CREB1; NCOA1; ASCL1; TCEA1; COPS2; DLX5; PSIP1; AEBP1; KLF9; ATF5; CITED2; XBP1; ID1; MYCN; ING2; PBX1; BBX; TAF9B; ZNF665; ID4; PAWR; TCF7L2; HOXC6; BMI1; BCL11B; ASH2L; NR2C1; MYRF; HIVEP2; JUND; TRIM22; FOXN3; MAF; GTF3A; GATA6; NRBF2; CTBP2; CREB3L1; ZFPM2; RYBP; ZNF532; NFAT5; TRIB3; ZNF232; LIN28A; ZEB1; SFPQ; SOX10; HIRA; MAGED1; ELF4; MXI1; PBX3; TOX; MAFB; BTG1; ZNF423; HOXB7; TGFB1I1; FOXO4; ZNF165; DAXX