Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24847 Pd-0325901 GSE70138 SKL Human 24h 10uM EID0061
Types Number Response transcription factors
Up-regulation 60 SOX4; NFKBIA; SMAD1; MDM2; MKL2; PDLIM1; BPTF; VEZF1; TLE1; SMARCA4; NFIL3; CTR9; RREB1; BRD2; JUN; ID2; SMAD6; MSX1; TCF7; REPIN1; TOB1; ABL1; ARID5B; FOXO1; TAL1; OSR2; TCF12; POU4F1; SMAD2; BCL11B; RRN3; CARHSP1; BRD4; LHX6; BRD8; TCEB2; ZNF160; VDR; ZMYM2; SPEN; SHOX2; MECOM; EYA2; ZMIZ1; ZBED1; LEF1; ESR1; SIAH2; CRYM; NKX3-1; ID3; SMAD7; SNAI2; PIR; KLF4; VGLL4; MAFB; EMX2; BMI1; HMG20B
Down-regulation 71 ETV1; NRIP1; EGR3; CREG1; BHLHE41; NAB2; FOSL1; ZNF117; NPM1; CITED2; CALR; HMGA2; SPIB; E2F3; EGR1; BLZF1; TRAK1; HIPK3; IL16; CTBP2; STAT4; PKNOX2; HMBOX1; EPAS1; LOXL2; NR4A1; TRIB3; RBPMS; PBX1; APEX1; BAZ2B; MEF2C; PLAGL1; EGR2; FOXC1; AHR; NFIB; WT1; HES1; ZSCAN18; BLM; TAF9B; TGFB1; ZIC3; NEUROD1; MYCN; WWC1; TCF21; TSC22D1; ZBTB18; NR4A2; ZHX2; GATA6; SOX10; ZFPM2; IRF8; TFAP2C; LIN28A; NR2F1; SALL2; HHEX; RUNX3; NFE2; WWTR1; HIC2; VPS72; PBX3; TRPS1; ZBED2; ZNF165; GATA3