Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24845 Osimertinib GSE70138 SKL Human 24h 0.12uM EID0061
Types Number Response transcription factors
Up-regulation 39 KDM5A; NR0B1; GATA2; HMGB1; VPS72; RBPMS; HOXD11; SETDB1; SSBP2; NFIC; ZSCAN18; KLF9; NR2F6; FOXM1; ISL1; ZNF232; FOXF1; NEUROD1; TTF2; HOXD1; SOX11; MEIS1; SUPT3H; IFI16; NFATC4; NKX2-2; ETS1; WT1; TWIST1; NANOG; LIN28A; ZBED2; ZFPM2; ID1; PEG3; NR2F1; ID4; ATF3; MEIS2
Down-regulation 32 TRIB3; HSF2; DDX54; XBP1; ZBTB18; HDAC4; REPIN1; BIRC2; EYA2; SIAH2; CREB3L1; SMARCA2; ZNF593; FOXO1; EGR3; TBL1X; NR2F2; MED1; MYB; MAF; LMCD1; BATF; LEF1; TOX3; HMGA1; ZBTB38; BTG1; HOXC6; BASP1; KDM5D; RELB; GATA3