Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24841	Osimertinib	GSE70138	SKL	Human	24h	10uM	EID0061

Response Information :

Types	Number	Response transcription factors
Up-regulation	49	FOSL1; ETV1; NCOA3; NFKBIA; IRF7; SP110; HMGA2; CD3D; TOB1; E2F6; BHLHE40; STAT1; IRF9; SP100; SP140L; RERE; RCOR3; DNMT3B; DDIT3; NAB2; TSC22D3; PHF20; TRIM22; NFIL3; ARNTL2; AFF1; RNF6; SREBF1; ELK3; TBL1X; ZMYND8; HMGA1; RBPJ; BATF3; NKX3-1; HOXB2; IFI16; ZMIZ1; ZNF217; CITED2; IRF1; PIR; TRIM16; HOXC10; SOX9; PSIP1; HOXC6; MECOM; ATF5
Down-regulation	54	NRIP1; MEF2C; MYCBP; ZNF135; ERBB2; JUN; COPS5; ZSCAN18; ERG; SMARCB1; ID3; HEY2; ZNF551; XBP1; PKNOX2; BACH2; TLE4; RRN3; TCF3; ZSCAN16; TCF4; UBE2L3; FLI1; EGR3; PTRF; SMAD1; SMAD3; CUX2; ID4; LHX2; MYT1L; TLE1; APEX1; ZEB2; IKBKAP; ZNF512B; SUB1; SOX10; PRKDC; PBX1; DACH1; LMCD1; SOX17; TBX3; PAX5; NR4A2; HEY1; FOSB; ZBED2; SOX11; LEF1; ECD; PEG3; GATA3