Transcriptional response

Response ID Perturbagen Data accession Cell Source Species Duration Concentration Expression ID
RID24831 Motesanib GSE70138 SKL Human 24h 1.11uM EID0061
Types Number Response transcription factors
Up-regulation 25 ZNF589; GATA2; YWHAB; FOSL2; VEZF1; MNT; PIR; LEF1; RORA; FLNA; RBBP4; NR1H2; ELK3; SFPQ; KLF10; NR1D2; HLTF; TGFB1; SMAD3; MSX1; MAFB; KLF2; ZEB2; HOXC6; KDM5D
Down-regulation 46 CREB3; ARNT2; SIX3; ZNF711; HMGA2; NR2F6; ST18; SOX3; GRHL2; GATA6; JAK2; KLF1; NR5A2; MYRF; CTBP2; GMNN; ZBED2; FOXA2; CBFA2T3; TCF7L1; ZIC3; TP63; POU4F1; ATF5; ELF4; EHF; ZFP36L2; SOX9; MYBL1; INSM1; BCL11A; IRF6; E2F8; TRPS1; TFAP2A; TOX; DLX2; VPS72; ZFPM2; SOX2; MYB; FOXG1; ATF3; HIRA; DAXX; GATA3