Transcriptional response

Meta Information :

Response ID	Perturbagen	Data accession	Cell Source	Species	Duration	Concentration	Expression ID
RID24791	Ibrutinib	GSE70138	SKL	Human	24h	0.12uM	EID0061

Response Information :

Types	Number	Response transcription factors
Up-regulation	67	L3MBTL1; PPARG; GATA2; ZNF711; CLOCK; MLXIPL; SMAD6; ZNF43; RRN3; MECOM; TXNIP; MDFI; ZNF331; PHF1; RBM39; ZNF117; ZNF107; SIM2; ZNF623; MKL2; HLX; CARHSP1; ZNF423; LITAF; DEK; TAL1; ZNF91; CCNE1; ZNF195; ZNF268; CHD7; ERBB4; ZNF85; ZNF93; AFF1; BCL11A; ZNF239; CBX7; CHD9; KLF9; PBX3; ID1; TFDP2; NFATC3; ZFPM2; CERS6; ID3; ZEB1; GATA6; GLI2; AEBP1; MNDA; TCF7; KAT2B; ID4; INSM1; TRPS1; TWIST1; LEF1; TCF4; MXI1; ASCL1; MYBL1; HIRA; POU2AF1; MEIS2; PEG3
Down-regulation	41	SMAD1; PPARGC1A; RNF141; HOXA1; SUB1; CHD4; HOXC10; PIAS2; NR2F2; VGLL4; HOXC6; EGR3; BIRC2; SMARCA2; ELK3; SIX1; RBPMS; RNF6; KAT7; ATF4; NRBF2; CITED2; CALR; CITED1; EYA2; BCL3; SIAH2; FOXC1; HOXB7; ELF3; IRX5; MAGED1; ZFP36L1; FOXD1; ZEB2; PSIP1; RUNX3; ETS2; MAFB; ZBTB18; TOX